node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFA40795.1 | SFA40801.1 | SAMN05216169_10042 | SAMN05216169_10043 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs. | Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains. | 0.614 |
SFA40795.1 | dapB | SAMN05216169_10042 | SAMN05216169_10041 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.919 |
SFA40795.1 | guaA | SAMN05216169_10042 | SAMN05216169_10954 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.675 |
SFA40801.1 | SFA40795.1 | SAMN05216169_10043 | SAMN05216169_10042 | Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains. | NTP pyrophosphatase, house-cleaning of non-canonical NTPs. | 0.614 |
SFA40801.1 | SFA44939.1 | SAMN05216169_10043 | SAMN05216169_101045 | Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains. | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.555 |
SFA40801.1 | dapB | SAMN05216169_10043 | SAMN05216169_10041 | Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.614 |
SFA40801.1 | guaA | SAMN05216169_10043 | SAMN05216169_10954 | Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.559 |
SFA44939.1 | SFA40801.1 | SAMN05216169_101045 | SAMN05216169_10043 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains. | 0.555 |
SFA44939.1 | guaA | SAMN05216169_101045 | SAMN05216169_10954 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.982 |
dapB | SFA40795.1 | SAMN05216169_10041 | SAMN05216169_10042 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | NTP pyrophosphatase, house-cleaning of non-canonical NTPs. | 0.919 |
dapB | SFA40801.1 | SAMN05216169_10041 | SAMN05216169_10043 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains. | 0.614 |
dapB | guaA | SAMN05216169_10041 | SAMN05216169_10954 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.459 |
guaA | SFA40795.1 | SAMN05216169_10954 | SAMN05216169_10042 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | NTP pyrophosphatase, house-cleaning of non-canonical NTPs. | 0.675 |
guaA | SFA40801.1 | SAMN05216169_10954 | SAMN05216169_10043 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains. | 0.559 |
guaA | SFA44939.1 | SAMN05216169_10954 | SAMN05216169_101045 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.982 |
guaA | dapB | SAMN05216169_10954 | SAMN05216169_10041 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.459 |