STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (265 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase ProB; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.936
ocd
Ornithine cyclodeaminase Ocd.
   
 
 0.875
proA
Gamma-glutamyl phosphate reductase ProA; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.770
KNF08720.1
Pyridoxal phosphate enzyme YggS family; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
 0.722
ywdH
Putative aldehyde dehydrogenase YwdH; Belongs to the aldehyde dehydrogenase family.
   
 
 0.654
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.564
KNF09370.1
DNA internalization-like competence protein ComEC/Rec2.
     
 0.544
pfl
Formate acetyltransferase Pfl.
    
 0.539
KNF07640.1
NADH:flavin oxidoreductase, Old yellow enzyme family.
  
  
 0.538
ddh
D-2-hydroxyacid dehydrogenase Ddh; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.534
Your Current Organism:
Gottschalkia purinilytica
NCBI taxonomy Id: 1503
Other names: ATCC 33906, Clostridium purinilyticum, Clostridium purinolyticum, G. purinilytica, strain WA-1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.