STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lgt2Prolipoprotein diacylglyceryl transferase Lgt; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. (193 aa)    
Predicted Functional Partners:
resA
Thiol-disulfide oxidoreductase ResA.
       0.778
ccdA
Cytochrome c-type biogenesis protein CcdA.
       0.749
trpA
Tryptophan synthase alpha chain TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
    0.741
trpB
Tryptophan synthase beta chain TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
    0.736
hprK
HPr kinase/phosphorylase HprK; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable c [...]
  
  
 0.508
yidC
Inner membrane protein translocase component YidC.
  
  
 0.495
oxaA1
Inner membrane insertion protein OxaA.
  
  
 0.495
gpsA
Glycerol-3-phosphate dehydrogenase GpsA; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
    0.474
KNF07603.1
Two-component system signal transduction histidine kinase.
  
    0.464
alr
Alanine racemase Alr; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
    0.460
Your Current Organism:
Gottschalkia purinilytica
NCBI taxonomy Id: 1503
Other names: ATCC 33906, Clostridium purinilyticum, Clostridium purinolyticum, G. purinilytica, strain WA-1
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