STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (395 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.998
hemL2
Glutamate-1-semialdehyde 2,1-aminomutase 2.
 
 0.991
hemD
Porphyrin biosynthesis protein HemD.
 
  
 0.978
sirC
Precorrin-2 dehydrogenase SirC.
 
  
 0.958
hemB
Delta-aminolevulinic acid dehydratase HemB; Belongs to the ALAD family.
 
  
 0.938
cbiL
Cobalt-precorrin-2 C(20)-methyltransferase CbiL; Belongs to the precorrin methyltransferase family.
 
   
 0.893
KNF07693.1
Putative pyridoxal phosphate-dependent acyltransferase.
     
 0.886
cbiJ
cobalt-precorrin-6A reductase CbiJ.
     
 0.873
cbiX
Cobalamin (vitamin B12) biosynthesis protein CbiX.
 
  
 0.869
cbiF
Cobalt-precorrin-4 C(11)-methyltransferase CbiF; Belongs to the precorrin methyltransferase family.
 
   
 0.869
Your Current Organism:
Gottschalkia purinilytica
NCBI taxonomy Id: 1503
Other names: ATCC 33906, Clostridium purinilyticum, Clostridium purinolyticum, G. purinilytica, strain WA-1
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