STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grdBGlycine reductase complex component B subunit gamma. (436 aa)    
Predicted Functional Partners:
grdA
Glycine/sarcosine/betaine reductase complex component A; In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination.
 
  
 0.954
grdE
Glycine reductase complex component B subunit alpha and beta.
 
  
 0.937
grdC
Glycine/sarcosine/betaine reductase complex component C subunit beta.
 
   
 0.877
grdD
Glycine/sarcosine/betaine reductase complex component C subunit alpha; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
   
 0.876
grdI
Betaine reductase complex component B subunit alpha.
 
  
 0.867
grdX
Gylcine reductase operon associated protein GrdX.
 
   
 0.834
trxA
Thioredoxin TrxA; Belongs to the thioredoxin family.
 
   
 0.817
trxB
Thioredoxin reductase TrxB.
 
   
 0.619
KNF07195.1
Protein of unknown function DUF3343; Hypothetical protein DUF3343.
  
     0.486
Your Current Organism:
Gottschalkia purinilytica
NCBI taxonomy Id: 1503
Other names: ATCC 33906, Clostridium purinilyticum, Clostridium purinolyticum, G. purinilytica, strain WA-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.