speA1 protein (Gottschalkia purinilytica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

speA1

Arginine decarboxylase SpeA. (473 aa)

Predicted Functional Partners:

tmk

0.741

speE-2

0.708

speB

0.653

KNF08915.1

0.590

KNF09227.1

0.547

KNF09829.1

0.507

argH

0.489

speE

0.460

KNF10071.1

0.450

argD

0.450

Your Current Organism:

Gottschalkia purinilytica

NCBI taxonomy Id: 1503
Other names: ATCC 33906, Clostridium purinilyticum, Clostridium purinolyticum, G. purinilytica, strain WA-1

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KNF08915.1	speA1	CLPU_5c02220	CLPU_2c02830	Cystathionine beta-lyase family protein.	Arginine decarboxylase SpeA.	0.590
KNF08915.1	speE	CLPU_5c02220	CLPU_13c00570	Cystathionine beta-lyase family protein.	Polyamine aminopropyl transferase SpeE.	0.420
KNF09227.1	speA1	CLPU_3c00050	CLPU_2c02830	Radical SAM domain protein.	Arginine decarboxylase SpeA.	0.547
KNF09227.1	speE	CLPU_3c00050	CLPU_13c00570	Radical SAM domain protein.	Polyamine aminopropyl transferase SpeE.	0.470
KNF09829.1	speA1	CLPU_2c02810	CLPU_2c02830	Hypothetical protein.	Arginine decarboxylase SpeA.	0.507
KNF09829.1	tmk	CLPU_2c02810	CLPU_2c02820	Hypothetical protein.	Thymidylate kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.778
KNF10071.1	argH	CLPU_1c02360	CLPU_9c00010	Lumazine-binding domain-containing protein.	Argininosuccinate lyase ArgH.	0.792
KNF10071.1	speA1	CLPU_1c02360	CLPU_2c02830	Lumazine-binding domain-containing protein.	Arginine decarboxylase SpeA.	0.450
KNF10071.1	speB	CLPU_1c02360	CLPU_2c02400	Lumazine-binding domain-containing protein.	Agmatinase SpeB; Belongs to the arginase family.	0.696
KNF10071.1	speE	CLPU_1c02360	CLPU_13c00570	Lumazine-binding domain-containing protein.	Polyamine aminopropyl transferase SpeE.	0.450
KNF10071.1	speE-2	CLPU_1c02360	CLPU_2c02410	Lumazine-binding domain-containing protein.	Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.	0.494
argD	argH	CLPU_3c01590	CLPU_9c00010	Acetylornithine aminotransferase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	Argininosuccinate lyase ArgH.	0.840
argD	speA1	CLPU_3c01590	CLPU_2c02830	Acetylornithine aminotransferase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	Arginine decarboxylase SpeA.	0.450
argD	speB	CLPU_3c01590	CLPU_2c02400	Acetylornithine aminotransferase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	Agmatinase SpeB; Belongs to the arginase family.	0.696
argD	speE	CLPU_3c01590	CLPU_13c00570	Acetylornithine aminotransferase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	Polyamine aminopropyl transferase SpeE.	0.450
argD	speE-2	CLPU_3c01590	CLPU_2c02410	Acetylornithine aminotransferase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.	0.494
argH	KNF10071.1	CLPU_9c00010	CLPU_1c02360	Argininosuccinate lyase ArgH.	Lumazine-binding domain-containing protein.	0.792
argH	argD	CLPU_9c00010	CLPU_3c01590	Argininosuccinate lyase ArgH.	Acetylornithine aminotransferase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	0.840
argH	speA1	CLPU_9c00010	CLPU_2c02830	Argininosuccinate lyase ArgH.	Arginine decarboxylase SpeA.	0.489
argH	speB	CLPU_9c00010	CLPU_2c02400	Argininosuccinate lyase ArgH.	Agmatinase SpeB; Belongs to the arginase family.	0.831