STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumAFumarate hydratase class I, aerobic. (183 aa)    
Predicted Functional Partners:
KNF09835.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily.
 
 0.998
KNF09833.1
NAD-dependent malic enzyme.
 
 
 0.991
aprA
Adenylylsulfate reductase, subunit alpha.
  
 
 0.828
ldh
L-lactate dehydrogenase Ldh; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.826
sfrB
NADPH-Fe(3+) oxidoreductase subunit beta.
    
 0.693
icd
Isocitrate dehydrogenase Icd; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
  
 0.684
nifJ
Pyruvate-flavodoxin oxidoreductase NifJ.
     
 0.672
nifJ-2
Pyruvate-flavodoxin oxidoreductase NifJ.
     
 0.672
gcvPB
Putative glycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
   
    0.655
argH
Argininosuccinate lyase ArgH.
    
 0.627
Your Current Organism:
Gottschalkia purinilytica
NCBI taxonomy Id: 1503
Other names: ATCC 33906, Clostridium purinilyticum, Clostridium purinolyticum, G. purinilytica, strain WA-1
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