Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KNF09835.1Hydro-lyase, Fe-S type, tartrate/fumarate subfamily. (280 aa)    
Predicted Functional Partners:
fumA
Fumarate hydratase class I, aerobic.
 0.999
KNF09833.1
NAD-dependent malic enzyme.
  
 
 0.930
aprA
Adenylylsulfate reductase, subunit alpha.
  
 
 0.913
ldh
L-lactate dehydrogenase Ldh; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.903
pyc
Pyruvate carboxylase Pyc; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.807
ywdH
Putative aldehyde dehydrogenase YwdH; Belongs to the aldehyde dehydrogenase family.
   
 
 0.770
nadB
L-aspartate oxidase NadB; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
  0.764
pfl
Formate acetyltransferase Pfl.
     
 0.757
argH
Argininosuccinate lyase ArgH.
    
  0.755
sfrB
NADPH-Fe(3+) oxidoreductase subunit beta.
    
 0.705
Your Current Organism:
Gottschalkia purinilytica
NCBI taxonomy Id: 1503
Other names: ATCC 33906, Clostridium purinilyticum, Clostridium purinolyticum, G. purinilytica, strain WA-1
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