KNF08979.1 protein (Gottschalkia purinilytica)

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Score

KNF08979.1

Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase. (595 aa)

Predicted Functional Partners:

metH4

0.999

metH

0.999

mtbC

0.992

metA

0.982

metH2

0.976

mtbC2

0.972

mtbC2-2

0.965

hom

0.956

metK

0.946

metK-2

0.946

Your Current Organism:

Gottschalkia purinilytica

NCBI taxonomy Id: 1503
Other names: ATCC 33906, Clostridium purinilyticum, Clostridium purinolyticum, G. purinilytica, strain WA-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KNF08979.1	hom	CLPU_4c00250	CLPU_15c00420	Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.	Homoserine dehydrogenase Hom.	0.956
KNF08979.1	metA	CLPU_4c00250	CLPU_1c01520	Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.	Homoserine O-succinyltransferase MetA; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	0.982
KNF08979.1	metH	CLPU_4c00250	CLPU_21c00330	Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.999
KNF08979.1	metH2	CLPU_4c00250	CLPU_18c00050	Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.	Vitamin B12-dependent methionine synthase MetH.	0.976
KNF08979.1	metH4	CLPU_4c00250	CLPU_18c00060	Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.	Methionine synthase.	0.999
KNF08979.1	metK	CLPU_4c00250	CLPU_2c01320	Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.	S-adenosylmethionine synthase MetK; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.946
KNF08979.1	metK-2	CLPU_4c00250	CLPU_7c00560	Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.	S-adenosylmethionine synthase MetK; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.946
KNF08979.1	mtbC	CLPU_4c00250	CLPU_14c00330	Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.	Dimethylamine corrinoid protein 1.	0.992
KNF08979.1	mtbC2	CLPU_4c00250	CLPU_10c00280	Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.	Dimethylamine corrinoid protein 2.	0.972
KNF08979.1	mtbC2-2	CLPU_4c00250	CLPU_4c01530	Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.	Dimethylamine corrinoid protein 2.	0.965
hom	KNF08979.1	CLPU_15c00420	CLPU_4c00250	Homoserine dehydrogenase Hom.	Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.	0.956
hom	metA	CLPU_15c00420	CLPU_1c01520	Homoserine dehydrogenase Hom.	Homoserine O-succinyltransferase MetA; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	0.896
hom	metH	CLPU_15c00420	CLPU_21c00330	Homoserine dehydrogenase Hom.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.931
hom	metH2	CLPU_15c00420	CLPU_18c00050	Homoserine dehydrogenase Hom.	Vitamin B12-dependent methionine synthase MetH.	0.524
hom	metH4	CLPU_15c00420	CLPU_18c00060	Homoserine dehydrogenase Hom.	Methionine synthase.	0.931
metA	KNF08979.1	CLPU_1c01520	CLPU_4c00250	Homoserine O-succinyltransferase MetA; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.	0.982
metA	hom	CLPU_1c01520	CLPU_15c00420	Homoserine O-succinyltransferase MetA; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	Homoserine dehydrogenase Hom.	0.896
metA	metH	CLPU_1c01520	CLPU_21c00330	Homoserine O-succinyltransferase MetA; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.797
metA	metH2	CLPU_1c01520	CLPU_18c00050	Homoserine O-succinyltransferase MetA; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	Vitamin B12-dependent methionine synthase MetH.	0.417
metA	metH4	CLPU_1c01520	CLPU_18c00060	Homoserine O-succinyltransferase MetA; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	Methionine synthase.	0.797