STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase-3 nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)    
Predicted Functional Partners:
hypB
Hydrogenase nickel incorporation protein HypB.
 
 
 0.973
sfrB
NADPH-Fe(3+) oxidoreductase subunit beta.
 
   
 0.928
KNF08482.1
Hypothetical protein.
 
     0.874
mrp
Protein Mrp; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
   0.813
KNF08688.1
Hypothetical protein.
  
 
 0.730
KNF07234.1
Hydrogenase maturation factor.
 
  
 0.719
flgD
Flagellar basal body rod modification protein FlgD.
    
   0.610
nifJ
Pyruvate-flavodoxin oxidoreductase NifJ.
     
 0.564
nifJ-2
Pyruvate-flavodoxin oxidoreductase NifJ.
     
 0.564
rnfB
Electron transport complex protein, subunit B; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
  
  
 0.542
Your Current Organism:
Gottschalkia purinilytica
NCBI taxonomy Id: 1503
Other names: ATCC 33906, Clostridium purinilyticum, Clostridium purinolyticum, G. purinilytica, strain WA-1
Server load: low (22%) [HD]