STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESCO_006596Uncharacterized protein. (1061 aa)    
Predicted Functional Partners:
ESCO_000603
Transcription-associated protein 1; Belongs to the PI3/PI4-kinase family.
   
 
 0.800
ESCO_002995
SAGA complex subunit spt3.
    
 
 0.796
ESCO_000549
Chromatin-remodeling complexes subunit NGG1.
    
 
 0.792
ESCO_000281
Transcription initiation factor TFIID subunit 9.
   
 
 0.779
ESCO_003427
SAGA-associated factor 29.
    
 
 0.778
ESCO_004204
Uncharacterized protein.
    
 
 0.772
ESCO_002812
Transcription initiation factor TFIID subunit 12.
    
 
 0.759
ESCO_003390
Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]
    
 
 0.759
ESCO_005384
Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
    
 
 0.663
ESCO_003288
Uncharacterized protein.
    
   0.647
Your Current Organism:
Escovopsis weberi
NCBI taxonomy Id: 150374
Other names: ATCC 64542, E. weberi
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