STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESCO_001231Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1681 aa)    
Predicted Functional Partners:
ESCO_006372
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
   
 0.999
ESCO_006041
UBA domain-containing protein 7.
   
 0.997
ESCO_003176
Rho-type GTPase-activating protein 1.
    
 0.975
ESCO_006367
AP-1 complex subunit gamma.
   
 0.974
ESCO_001608
Endocytosis protein end4.
    
 0.967
ESCO_005338
Phosphatidylinositol 3.
    
 0.956
ESCO_001863
AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family.
   
 0.934
ESCO_001958
Protein hob3.
    
 
 0.934
ESCO_005695
Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
    
 0.933
ESCO_006484
Epsin-3.
    
 0.925
Your Current Organism:
Escovopsis weberi
NCBI taxonomy Id: 150374
Other names: ATCC 64542, E. weberi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.