STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoVADUnannotated protein. (342 aa)    
Predicted Functional Partners:
spoVAC
Unannotated protein.
 
  
 0.990
spoVAE
Unannotated protein.
 
  
 0.982
spoIIAB
Unannotated protein; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
  
 0.921
gpr
Unannotated protein; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.920
sigF
Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.887
spoIIAA
Unannotated protein; Belongs to the anti-sigma-factor antagonist family.
 
   
 0.875
CP523_11425
Unannotated protein.
 
  
 0.855
spo0A
Unannotated protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.846
spoVT
Unannotated protein.
  
   
 0.815
CP523_11060
Unannotated protein.
  
  
 0.807
Your Current Organism:
Clostridium septicum
NCBI taxonomy Id: 1504
Other names: ATCC 12464, BCRC 14552, Bacillus septicus, C. septicum, CCM 5743, CCRC 14552, CCRC:14552, CCUG 4855, CIP 61.10, CN 3790, DSM 7534, JCM 8144, NCCB 47070, NCIMB 547, NCTC 547, NRRL B-3197, Vibrio septicus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.