STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prmAUnannotated protein; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (313 aa)    
Predicted Functional Partners:
CP523_02245
Unannotated protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
  
  
 0.931
mtaB
Unannotated protein.
  
    0.918
dnaJ
Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]
  
  
 0.773
rplK
Unannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
 
 0.745
CP523_02235
Unannotated protein.
       0.716
rpsU
Unannotated protein; Belongs to the bacterial ribosomal protein bS21 family.
     
 0.685
CP523_02225
Unannotated protein.
 
     0.681
rsmB
Unannotated protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
  
 0.624
era
Unannotated protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
     
 0.615
CP523_14065
Unannotated protein.
  
  
 0.588
Your Current Organism:
Clostridium septicum
NCBI taxonomy Id: 1504
Other names: ATCC 12464, BCRC 14552, Bacillus septicus, C. septicum, CCM 5743, CCRC 14552, CCRC:14552, CCUG 4855, CIP 61.10, CN 3790, DSM 7534, JCM 8144, NCCB 47070, NCIMB 547, NCTC 547, NRRL B-3197, Vibrio septicus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.