STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFD45555.1Uncharacterized membrane protein HdeD, DUF308 family. (180 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
  0.928
SFD42146.1
Signal transduction histidine kinase.
  
 0.920
SFD46611.1
Signal transduction histidine kinase.
  
 0.920
SFD53133.1
Two-component system, CitB family, sensor histidine kinase MalK.
  
 0.920
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
   
   0.726
SFD45667.1
Protein of unknown function.
  
  
  0.690
SFD28292.1
Protein of unknown function.
  
 
 0.669
uvrA
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
       0.645
SFD29113.1
Calcineurin-like phosphoesterase.
  
  
  0.636
SFD46758.1
Helix-turn-helix domain-containing protein.
  
 
 0.625
Your Current Organism:
Lactobacillus bombicola
NCBI taxonomy Id: 1505723
Other names: DSM 28793, L. bombicola, LMG 28288, LMG:28288, Lactobacillus bombicola Praet et al. 2015, Lactobacillus sp. R-53102, strain R-53102
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