B0A48_18627 protein (Rachicladosporium antarcticum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

B0A48_18627

Zn(2)-C6 fungal-type domain-containing protein. (481 aa)

Predicted Functional Partners:

B0A48_05216

0.798

B0A48_01857

0.798

B0A48_17693

0.722

B0A48_09958

0.722

B0A48_12122

0.716

B0A48_09152

0.716

B0A48_12522

0.704

B0A48_03662

0.704

B0A48_08008

0.662

B0A48_02806

0.662

Your Current Organism:

Rachicladosporium antarcticum

NCBI taxonomy Id: 1507870
Other names: CCFEE 5527, R. antarcticum, Rachicladosporium antarcticum Onofri & Egidi, 2014

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A48_01857	B0A48_02806	A0A1V8TQT8	A0A1V8TLC8	CBFD_NFYB_HMF domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.423
B0A48_01857	B0A48_08008	A0A1V8TQT8	A0A1V8T0Z1	CBFD_NFYB_HMF domain-containing protein.	Uncharacterized protein.	0.423
B0A48_01857	B0A48_18627	A0A1V8TQT8	A0A1V8S7I3	CBFD_NFYB_HMF domain-containing protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.798
B0A48_02806	B0A48_01857	A0A1V8TLC8	A0A1V8TQT8	CBFD_NFYB_HMF domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.423
B0A48_02806	B0A48_03662	A0A1V8TLC8	A0A1V8TKP0	CBFD_NFYB_HMF domain-containing protein.	Uncharacterized protein.	0.447
B0A48_02806	B0A48_05216	A0A1V8TLC8	A0A1V8TI91	CBFD_NFYB_HMF domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.423
B0A48_02806	B0A48_09152	A0A1V8TLC8	A0A1V8T256	CBFD_NFYB_HMF domain-containing protein.	Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.	0.421
B0A48_02806	B0A48_09958	A0A1V8TLC8	A0A1V8T374	CBFD_NFYB_HMF domain-containing protein.	SGF29 C-terminal domain-containing protein.	0.471
B0A48_02806	B0A48_12122	A0A1V8TLC8	A0A1V8SU75	CBFD_NFYB_HMF domain-containing protein.	Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.	0.421
B0A48_02806	B0A48_12522	A0A1V8TLC8	A0A1V8SSK8	CBFD_NFYB_HMF domain-containing protein.	Uncharacterized protein.	0.447
B0A48_02806	B0A48_17693	A0A1V8TLC8	A0A1V8SAL7	CBFD_NFYB_HMF domain-containing protein.	SGF29 C-terminal domain-containing protein.	0.471
B0A48_02806	B0A48_18627	A0A1V8TLC8	A0A1V8S7I3	CBFD_NFYB_HMF domain-containing protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.662
B0A48_03662	B0A48_02806	A0A1V8TKP0	A0A1V8TLC8	Uncharacterized protein.	CBFD_NFYB_HMF domain-containing protein.	0.447
B0A48_03662	B0A48_08008	A0A1V8TKP0	A0A1V8T0Z1	Uncharacterized protein.	Uncharacterized protein.	0.447
B0A48_03662	B0A48_09152	A0A1V8TKP0	A0A1V8T256	Uncharacterized protein.	Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.	0.993
B0A48_03662	B0A48_09958	A0A1V8TKP0	A0A1V8T374	Uncharacterized protein.	SGF29 C-terminal domain-containing protein.	0.987
B0A48_03662	B0A48_12122	A0A1V8TKP0	A0A1V8SU75	Uncharacterized protein.	Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.	0.993
B0A48_03662	B0A48_17693	A0A1V8TKP0	A0A1V8SAL7	Uncharacterized protein.	SGF29 C-terminal domain-containing protein.	0.987
B0A48_03662	B0A48_18627	A0A1V8TKP0	A0A1V8S7I3	Uncharacterized protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.704
B0A48_05216	B0A48_02806	A0A1V8TI91	A0A1V8TLC8	CBFD_NFYB_HMF domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.423

page 1 of 4

Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0038024

Cargo receptor activity

4 of 15

2.83

4.08

7.94e-08

GO:0008239

Dipeptidyl-peptidase activity

2 of 5

3.01

1.55

0.0024

GO:0008238

Exopeptidase activity

3 of 76

2.0

1.43

0.0024

GO:0005509

Calcium ion binding

4 of 274

1.57

1.24

0.0024

GO:0008233

Peptidase activity

4 of 484

1.32

0.9

0.0088

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:20699

Uptake of dietary cobalamins into enterocytes, and T-box superfamily

4 of 12

2.93

4.31

3.36e-08

CL:20666

Mixed, incl. Astacin-like metallopeptidase domain, and Sema domain superfamily

5 of 56

2.36

3.98

3.36e-08

CL:18416

Mixed, incl. Serine carboxypeptidase S28, and Dipeptidylpeptidase IV, N-terminal domain

3 of 7

3.04

3.51

9.98e-07

CL:20702

Uptake of dietary cobalamins into enterocytes, and T-box transcription factor

2 of 6

2.93

1.93

0.00051

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-196791

Vitamin D (calciferol) metabolism

4 of 8

3.11

4.76

6.79e-09

MAP-9758881

Uptake of dietary cobalamins into enterocytes

4 of 11

2.97

4.64

9.36e-09

MAP-196741

Cobalamin (Cbl, vitamin B12) transport and metabolism

4 of 20

2.71

4.14

4.85e-08

MAP-8964043

Plasma lipoprotein clearance

4 of 21

2.69

4.13

4.85e-08

MAP-174824

Plasma lipoprotein assembly, remodeling, and clearance

4 of 34

2.48

3.69

2.02e-07

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-1015

Disulfide bond

4 of 368

1.44

1.17

0.0022

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF05577

Serine carboxypeptidase S28

2 of 2

3.41

1.76

0.0011

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000859

CUB domain

4 of 46

2.35

2.75

1.02e-05

IPR035914

Spermadhesin, CUB domain superfamily

4 of 52

2.29

2.72

1.02e-05

IPR042269

Serine carboxypeptidase S28, SKS domain

2 of 3

3.23

1.61

0.0019

IPR008758

Peptidase S28

2 of 3

3.23

1.61

0.0019

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00042

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein.

4 of 41

2.4

3.32

8.41e-07

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (26%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About