B0A48_17731 protein (Rachicladosporium antarcticum)

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Coexpression

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Score

B0A48_17731

Mitochondrial import receptor subunit tom70. (628 aa)

Predicted Functional Partners:

B0A48_09403

0.991

B0A48_13884

0.976

B0A48_04877

0.976

B0A48_16591

0.969

B0A48_04596

0.969

B0A48_01352

0.966

B0A48_00181

0.966

B0A48_11270

0.863

B0A48_09057

0.863

B0A48_05447

0.784

Your Current Organism:

Rachicladosporium antarcticum

NCBI taxonomy Id: 1507870
Other names: CCFEE 5527, R. antarcticum, Rachicladosporium antarcticum Onofri & Egidi, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A48_00181	B0A48_01352	A0A1V8TTY5	A0A1V8TSZ0	Uncharacterized protein.	Uncharacterized protein.	0.543
B0A48_00181	B0A48_04596	A0A1V8TTY5	A0A1V8TG53	Uncharacterized protein.	Uncharacterized protein.	0.992
B0A48_00181	B0A48_04877	A0A1V8TTY5	A0A1V8TDK3	Uncharacterized protein.	Uncharacterized protein.	0.980
B0A48_00181	B0A48_05447	A0A1V8TTY5	A0A1V8TIX9	Uncharacterized protein.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.458
B0A48_00181	B0A48_09057	A0A1V8TTY5	A0A1V8T1T5	Uncharacterized protein.	J domain-containing protein.	0.954
B0A48_00181	B0A48_09403	A0A1V8TTY5	A0A1V8SWH5	Uncharacterized protein.	Uncharacterized protein.	0.999
B0A48_00181	B0A48_11270	A0A1V8TTY5	A0A1V8SV08	Uncharacterized protein.	J domain-containing protein.	0.954
B0A48_00181	B0A48_13884	A0A1V8TTY5	A0A1V8SLU7	Uncharacterized protein.	Uncharacterized protein.	0.980
B0A48_00181	B0A48_16591	A0A1V8TTY5	A0A1V8SE40	Uncharacterized protein.	Uncharacterized protein.	0.992
B0A48_00181	B0A48_17731	A0A1V8TTY5	A0A1V8S9H2	Uncharacterized protein.	Mitochondrial import receptor subunit tom70.	0.966
B0A48_01352	B0A48_00181	A0A1V8TSZ0	A0A1V8TTY5	Uncharacterized protein.	Uncharacterized protein.	0.543
B0A48_01352	B0A48_04596	A0A1V8TSZ0	A0A1V8TG53	Uncharacterized protein.	Uncharacterized protein.	0.992
B0A48_01352	B0A48_04877	A0A1V8TSZ0	A0A1V8TDK3	Uncharacterized protein.	Uncharacterized protein.	0.980
B0A48_01352	B0A48_05447	A0A1V8TSZ0	A0A1V8TIX9	Uncharacterized protein.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.458
B0A48_01352	B0A48_09057	A0A1V8TSZ0	A0A1V8T1T5	Uncharacterized protein.	J domain-containing protein.	0.954
B0A48_01352	B0A48_09403	A0A1V8TSZ0	A0A1V8SWH5	Uncharacterized protein.	Uncharacterized protein.	0.999
B0A48_01352	B0A48_11270	A0A1V8TSZ0	A0A1V8SV08	Uncharacterized protein.	J domain-containing protein.	0.954
B0A48_01352	B0A48_13884	A0A1V8TSZ0	A0A1V8SLU7	Uncharacterized protein.	Uncharacterized protein.	0.980
B0A48_01352	B0A48_16591	A0A1V8TSZ0	A0A1V8SE40	Uncharacterized protein.	Uncharacterized protein.	0.992
B0A48_01352	B0A48_17731	A0A1V8TSZ0	A0A1V8S9H2	Uncharacterized protein.	Mitochondrial import receptor subunit tom70.	0.966

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.879

expected number of edges:

10

PPI enrichment p-value:

1.31e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000819

Sister chromatid segregation

11 of 38

2.21

8.0

6.70e-21

GO:0000070

Mitotic sister chromatid segregation

10 of 33

2.23

7.5

6.92e-19

GO:0000280

Nuclear division

11 of 72

1.93

5.97

7.42e-19

GO:0007076

Mitotic chromosome condensation

5 of 5

2.75

5.01

3.38e-10

GO:0007062

Sister chromatid cohesion

5 of 15

2.27

3.82

1.68e-08

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003682

Chromatin binding

6 of 56

1.78

2.64

4.04e-07

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044815

DNA packaging complex

8 of 38

2.07

5.09

5.93e-13

GO:0000796

Condensin complex

5 of 5

2.75

4.98

3.78e-10

GO:0005694

Chromosome

10 of 235

1.38

2.4

3.14e-11

GO:0000793

Condensed chromosome

4 of 46

1.69

1.7

0.00015

GO:0008278

Cohesin complex

2 of 6

2.27

1.2

0.0059

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3358

Mixed, incl. AAA domain, and Sister chromatid cohesion

9 of 19

2.42

7.83

1.06e-17

CL:3383

Condensin complex

5 of 5

2.75

5.07

2.58e-10

CL:3136

DNA metabolic process

10 of 130

1.63

3.63

1.40e-13

CL:3359

Cohesin complex, and Smc5-Smc6 complex

4 of 12

2.27

2.96

1.40e-06

CL:3362

Mitotic cohesin complex, and Cohesin loading

3 of 5

2.53

2.42

2.92e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04111

Cell cycle - yeast

8 of 91

1.69

3.38

7.05e-11

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-68877

Mitotic Prometaphase

9 of 55

1.96

5.07

3.64e-14

MAP-2514853

Condensation of Prometaphase Chromosomes

5 of 9

2.49

4.43

2.14e-09

MAP-68886

M Phase

10 of 115

1.69

3.94

3.80e-14

MAP-69278

Cell Cycle, Mitotic

10 of 198

1.45

2.73

4.73e-12

MAP-1640170

Cell Cycle

10 of 246

1.36

2.34

2.93e-11

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000793

Condensed chromosome

7 of 35

2.05

4.4

5.52e-11

GOCC:0000796

Condensin complex

4 of 4

2.75

3.74

1.08e-07

GOCC:0005694

Chromosome

10 of 214

1.42

2.53

2.96e-11

GOCC:0008278

Cohesin complex

2 of 6

2.27

1.11

0.0086

GOCC:0032991

Protein-containing complex

9 of 1684

0.48

0.33

0.0231

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR016024

Armadillo-type fold

5 of 130

1.33

0.98

0.0039

IPR036277

SMCs flexible hinge superfamily

2 of 4

2.45

0.75

0.0430

IPR024704

Structural maintenance of chromosomes protein

2 of 4

2.45

0.75

0.0430

IPR010935

SMCs flexible hinge

2 of 4

2.45

0.75

0.0430

IPR003395

RecF/RecN/SMC, N-terminal

2 of 5

2.35

0.75

0.0430

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00968

SMC proteins Flexible Hinge Domain

2 of 4

2.45

1.06

0.0113

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