B0A48_16951 protein (Rachicladosporium antarcticum)

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

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[Homology]

Score

B0A48_16951

Uncharacterized protein. (966 aa)

Predicted Functional Partners:

B0A48_06112

0.724

B0A48_05683

0.596

B0A48_16949

0.542

B0A48_13414

0.542

B0A48_16270

0.511

B0A48_01941

0.511

B0A48_16429

0.508

B0A48_10267

0.508

B0A48_09647

0.508

B0A48_05010

0.508

Your Current Organism:

Rachicladosporium antarcticum

NCBI taxonomy Id: 1507870
Other names: CCFEE 5527, R. antarcticum, Rachicladosporium antarcticum Onofri & Egidi, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A48_01941	B0A48_13414	A0A1V8TR28	A0A1V8SQA8	SCA7 domain-containing protein.	Uncharacterized protein.	0.981
B0A48_01941	B0A48_16949	A0A1V8TR28	A0A1V8SCU7	SCA7 domain-containing protein.	Uncharacterized protein.	0.981
B0A48_01941	B0A48_16951	A0A1V8TR28	A0A1V8SD56	SCA7 domain-containing protein.	Uncharacterized protein.	0.511
B0A48_05010	B0A48_05683	A0A1V8TEE1	A0A1V8TBL6	Uridine kinase; Belongs to the uridine kinase family.	Uncharacterized protein.	0.995
B0A48_05010	B0A48_16951	A0A1V8TEE1	A0A1V8SD56	Uridine kinase; Belongs to the uridine kinase family.	Uncharacterized protein.	0.508
B0A48_05683	B0A48_05010	A0A1V8TBL6	A0A1V8TEE1	Uncharacterized protein.	Uridine kinase; Belongs to the uridine kinase family.	0.995
B0A48_05683	B0A48_06112	A0A1V8TBL6	A0A1V8TCW3	Uncharacterized protein.	Uncharacterized protein.	0.995
B0A48_05683	B0A48_09647	A0A1V8TBL6	A0A1V8T065	Uncharacterized protein.	Uracil phosphoribosyltransferase.	0.995
B0A48_05683	B0A48_10267	A0A1V8TBL6	A0A1V8SXH0	Uncharacterized protein.	Uracil phosphoribosyltransferase.	0.995
B0A48_05683	B0A48_16429	A0A1V8TBL6	A0A1V8SDZ9	Uncharacterized protein.	Uridine kinase; Belongs to the uridine kinase family.	0.995
B0A48_05683	B0A48_16951	A0A1V8TBL6	A0A1V8SD56	Uncharacterized protein.	Uncharacterized protein.	0.596
B0A48_06112	B0A48_05683	A0A1V8TCW3	A0A1V8TBL6	Uncharacterized protein.	Uncharacterized protein.	0.995
B0A48_06112	B0A48_16951	A0A1V8TCW3	A0A1V8SD56	Uncharacterized protein.	Uncharacterized protein.	0.724
B0A48_09647	B0A48_05683	A0A1V8T065	A0A1V8TBL6	Uracil phosphoribosyltransferase.	Uncharacterized protein.	0.995
B0A48_09647	B0A48_16951	A0A1V8T065	A0A1V8SD56	Uracil phosphoribosyltransferase.	Uncharacterized protein.	0.508
B0A48_10267	B0A48_05683	A0A1V8SXH0	A0A1V8TBL6	Uracil phosphoribosyltransferase.	Uncharacterized protein.	0.995
B0A48_10267	B0A48_16951	A0A1V8SXH0	A0A1V8SD56	Uracil phosphoribosyltransferase.	Uncharacterized protein.	0.508
B0A48_13414	B0A48_01941	A0A1V8SQA8	A0A1V8TR28	Uncharacterized protein.	SCA7 domain-containing protein.	0.981
B0A48_13414	B0A48_16270	A0A1V8SQA8	A0A1V8SFQ8	Uncharacterized protein.	SCA7 domain-containing protein.	0.981
B0A48_13414	B0A48_16951	A0A1V8SQA8	A0A1V8SD56	Uncharacterized protein.	Uncharacterized protein.	0.542

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

19

average node degree:

3.45

avg. local clustering coefficient:

0.745

expected number of edges:

25

PPI enrichment p-value:

0.911

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006544

Glycine metabolic process

7 of 29

2.35

5.59

1.86e-12

GO:0006545

Glycine biosynthetic process

5 of 20

2.37

3.95

1.37e-08

GO:0046654

Tetrahydrofolate biosynthetic process

5 of 22

2.32

3.89

1.56e-08

GO:0019464

Glycine decarboxylation via glycine cleavage system

2 of 4

2.67

1.64

0.00099

GO:0019438

Aromatic compound biosynthetic process

7 of 486

1.13

1.23

1.70e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004146

Dihydrofolate reductase activity

5 of 16

2.46

4.1

9.84e-09

GO:0050661

NADP binding

5 of 58

1.9

2.72

8.32e-07

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005960

Glycine cleavage complex

2 of 2

2.97

1.66

0.0010

GO:0005737

Cytoplasm

9 of 2624

0.5

0.36

0.0128

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:15381

Mixed, incl. Dihydrofolate reductase activity, and Activator of Hsp90 ATPase homologue 1-like, C-terminal

5 of 48

1.99

2.59

3.18e-06

CL:15383

Mixed, incl. Dihydrofolate reductase activity, and Pyridoxamine 5-phosphate oxidase

4 of 23

2.21

2.46

1.43e-05

CL:1963

One carbon pool by folate, and Glycine cleavage complex

3 of 14

2.3

1.87

0.00029

CL:2404

Ribose/Galactose Isomerase, and Pentose catabolic process

2 of 5

2.57

1.17

0.0072

CL:15387

Dihydrofolate reductase activity

2 of 5

2.57

1.17

0.0072

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

kphy01051

Biosynthesis of ansamycins

2 of 11

2.23

1.2

0.0056

kphy01200

Carbon metabolism

4 of 147

1.4

1.12

0.0019

kphy00030

Pentose phosphate pathway

2 of 31

1.78

0.82

0.0248

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005960

Glycine cleavage complex

2 of 2

2.97

1.47

0.0022

GOCC:0005829

Cytosol

6 of 908

0.79

0.48

0.0260

GOCC:0005737

Cytoplasm

9 of 2601

0.51

0.34

0.0260

GOCC:0005622

Intracellular

10 of 3615

0.41

0.29

0.0260

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01872

RibD C-terminal domain

4 of 17

2.34

2.77

4.41e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR024072

Dihydrofolate reductase-like domain superfamily

5 of 19

2.39

3.7

5.22e-08

IPR002734

Bacterial bifunctional deaminase-reductase, C-terminal

4 of 17

2.34

2.73

5.36e-06

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