B0A48_16024 protein (Rachicladosporium antarcticum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

B0A48_16024

Uncharacterized protein. (259 aa)

Predicted Functional Partners:

B0A48_11273

0.938

B0A48_09054

0.938

B0A48_10881

0.934

B0A48_08837

0.934

B0A48_17641

0.931

B0A48_15783

0.931

B0A48_12475

0.930

B0A48_03612

0.930

B0A48_13941

0.929

B0A48_10101

0.929

Your Current Organism:

Rachicladosporium antarcticum

NCBI taxonomy Id: 1507870
Other names: CCFEE 5527, R. antarcticum, Rachicladosporium antarcticum Onofri & Egidi, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A48_03612	B0A48_08837	A0A1V8TKI7	A0A1V8T4L3	Trafficking protein particle complex subunit BET3.	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	0.995
B0A48_03612	B0A48_09054	A0A1V8TKI7	A0A1V8T1L2	Trafficking protein particle complex subunit BET3.	Uncharacterized protein.	0.992
B0A48_03612	B0A48_10101	A0A1V8TKI7	A0A1V8SWT2	Trafficking protein particle complex subunit BET3.	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	0.995
B0A48_03612	B0A48_10881	A0A1V8TKI7	A0A1V8SYX3	Trafficking protein particle complex subunit BET3.	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	0.995
B0A48_03612	B0A48_11273	A0A1V8TKI7	A0A1V8SV88	Trafficking protein particle complex subunit BET3.	Uncharacterized protein.	0.992
B0A48_03612	B0A48_13941	A0A1V8TKI7	A0A1V8SM51	Trafficking protein particle complex subunit BET3.	Uncharacterized protein.	0.992
B0A48_03612	B0A48_15783	A0A1V8TKI7	A0A1V8SHA4	Trafficking protein particle complex subunit BET3.	Uncharacterized protein.	0.993
B0A48_03612	B0A48_16024	A0A1V8TKI7	A0A1V8SEX7	Trafficking protein particle complex subunit BET3.	Uncharacterized protein.	0.930
B0A48_03612	B0A48_17641	A0A1V8TKI7	A0A1V8SBF4	Trafficking protein particle complex subunit BET3.	Uncharacterized protein.	0.993
B0A48_08837	B0A48_03612	A0A1V8T4L3	A0A1V8TKI7	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	Trafficking protein particle complex subunit BET3.	0.995
B0A48_08837	B0A48_09054	A0A1V8T4L3	A0A1V8T1L2	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	Uncharacterized protein.	0.989
B0A48_08837	B0A48_10101	A0A1V8T4L3	A0A1V8SWT2	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	0.996
B0A48_08837	B0A48_11273	A0A1V8T4L3	A0A1V8SV88	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	Uncharacterized protein.	0.989
B0A48_08837	B0A48_12475	A0A1V8T4L3	A0A1V8SSX6	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	Trafficking protein particle complex subunit BET3.	0.995
B0A48_08837	B0A48_13941	A0A1V8T4L3	A0A1V8SM51	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	Uncharacterized protein.	0.988
B0A48_08837	B0A48_15783	A0A1V8T4L3	A0A1V8SHA4	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	Uncharacterized protein.	0.992
B0A48_08837	B0A48_16024	A0A1V8T4L3	A0A1V8SEX7	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	Uncharacterized protein.	0.934
B0A48_08837	B0A48_17641	A0A1V8T4L3	A0A1V8SBF4	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	Uncharacterized protein.	0.992
B0A48_09054	B0A48_03612	A0A1V8T1L2	A0A1V8TKI7	Uncharacterized protein.	Trafficking protein particle complex subunit BET3.	0.992
B0A48_09054	B0A48_08837	A0A1V8T1L2	A0A1V8T4L3	Uncharacterized protein.	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	0.989

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.731

expected number of edges:

12

PPI enrichment p-value:

1.63e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006534

Cysteine metabolic process

10 of 25

2.55

9.78

1.32e-21

GO:0019346

Transsulfuration

5 of 9

2.7

5.11

1.82e-10

GO:0006535

Cysteine biosynthetic process from serine

5 of 12

2.57

4.84

4.01e-10

GO:1901605

Alpha-amino acid metabolic process

11 of 169

1.76

4.79

2.16e-17

GO:1901566

Organonitrogen compound biosynthetic process

6 of 576

0.97

0.83

0.00076

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009001

Serine O-acetyltransferase activity

4 of 7

2.71

3.54

2.48e-07

GO:0102028

Cystathionine gamma-synthase activity (acts on O-phosphohomoserine)

3 of 3

2.95

3.06

2.57e-06

GO:0003962

Cystathionine gamma-synthase activity

3 of 3

2.95

3.06

2.57e-06

GO:0030170

Pyridoxal phosphate binding

5 of 49

1.96

2.9

4.15e-07

GO:0016765

Transferase activity, transferring alkyl or aryl (other than methyl) groups

4 of 46

1.89

2.22

1.70e-05

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 2163

0.66

0.61

9.66e-06

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7368

Cysteine biosynthetic process from serine, and Cystathionine gamma-synthase activity

7 of 13

2.68

7.15

9.12e-15

CL:7367

Sulfur amino acid metabolic process, and Methionine adenosyltransferase activity

8 of 25

2.46

7.02

1.99e-15

CL:7370

Cysteine biosynthetic process from serine

3 of 7

2.58

2.4

3.36e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00270

Cysteine and methionine metabolism

10 of 90

2.0

6.06

1.11e-17

map00450

Selenocompound metabolism

5 of 23

2.29

4.18

2.66e-09

map01230

Biosynthesis of amino acids

8 of 187

1.58

2.95

2.22e-10

map00920

Sulfur metabolism

4 of 65

1.74

2.08

1.60e-05

map01200

Carbon metabolism

4 of 160

1.35

1.25

0.00044

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0663

Pyridoxal phosphate

4 of 48

1.87

2.02

4.97e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00132

Bacterial transferase hexapeptide (six repeats)

3 of 13

2.31

1.75

0.00051

PF01053

Cys/Met metabolism PLP-dependent enzyme

2 of 4

2.65

1.17

0.0075

PF00155

Aminotransferase class I and II

2 of 14

2.11

0.75

0.0399

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000277

Cys/Met metabolism, pyridoxal phosphate-dependent enzyme

5 of 6

2.87

4.95

5.99e-10

IPR045304

Serine acetyltransferase, LbH domain

4 of 4

2.95

3.91

6.38e-08

IPR011004

Trimeric LpxA-like superfamily

4 of 17

2.32

2.86

2.71e-06

IPR005881

Serine O-acetyltransferase

3 of 3

2.95

2.77

8.96e-06

IPR015424

Pyridoxal phosphate-dependent transferase

5 of 49

1.96

2.71

1.34e-06

(more ...)

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