B0A48_13340 protein (Rachicladosporium antarcticum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

B0A48_13340

Uncharacterized protein. (506 aa)

Predicted Functional Partners:

B0A48_11276

0.784

B0A48_09051

0.784

B0A48_14598

0.654

B0A48_10669

0.654

B0A48_08599

0.649

B0A48_04368

0.649

B0A48_11812

0.639

B0A48_08537

0.639

B0A48_07592

0.639

B0A48_04292

0.639

Your Current Organism:

Rachicladosporium antarcticum

NCBI taxonomy Id: 1507870
Other names: CCFEE 5527, R. antarcticum, Rachicladosporium antarcticum Onofri & Egidi, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A48_04292	B0A48_04368	A0A1V8TEX9	A0A1V8TF61	Guanine nucleotide-binding protein subunit alpha.	Uncharacterized protein.	0.822
B0A48_04292	B0A48_07592	A0A1V8TEX9	A0A1V8T6I7	Guanine nucleotide-binding protein subunit alpha.	Guanine nucleotide-binding protein alpha-3 subunit.	0.863
B0A48_04292	B0A48_08599	A0A1V8TEX9	A0A1V8T6C6	Guanine nucleotide-binding protein subunit alpha.	Uncharacterized protein.	0.822
B0A48_04292	B0A48_11812	A0A1V8TEX9	A0A1V8STC6	Guanine nucleotide-binding protein subunit alpha.	Guanine nucleotide-binding protein alpha-3 subunit.	0.863
B0A48_04292	B0A48_13340	A0A1V8TEX9	A0A1V8SPL5	Guanine nucleotide-binding protein subunit alpha.	Uncharacterized protein.	0.639
B0A48_04368	B0A48_04292	A0A1V8TF61	A0A1V8TEX9	Uncharacterized protein.	Guanine nucleotide-binding protein subunit alpha.	0.822
B0A48_04368	B0A48_07592	A0A1V8TF61	A0A1V8T6I7	Uncharacterized protein.	Guanine nucleotide-binding protein alpha-3 subunit.	0.822
B0A48_04368	B0A48_08537	A0A1V8TF61	A0A1V8T5Z1	Uncharacterized protein.	Uncharacterized protein.	0.822
B0A48_04368	B0A48_09051	A0A1V8TF61	A0A1V8T1U8	Uncharacterized protein.	E3 ubiquitin-protein ligase.	0.800
B0A48_04368	B0A48_10669	A0A1V8TF61	A0A1V8SXZ2	Uncharacterized protein.	Uncharacterized protein.	0.663
B0A48_04368	B0A48_11276	A0A1V8TF61	A0A1V8SVT2	Uncharacterized protein.	E3 ubiquitin-protein ligase.	0.800
B0A48_04368	B0A48_11812	A0A1V8TF61	A0A1V8STC6	Uncharacterized protein.	Guanine nucleotide-binding protein alpha-3 subunit.	0.822
B0A48_04368	B0A48_13340	A0A1V8TF61	A0A1V8SPL5	Uncharacterized protein.	Uncharacterized protein.	0.649
B0A48_04368	B0A48_14598	A0A1V8TF61	A0A1V8SL26	Uncharacterized protein.	Uncharacterized protein.	0.663
B0A48_07592	B0A48_04292	A0A1V8T6I7	A0A1V8TEX9	Guanine nucleotide-binding protein alpha-3 subunit.	Guanine nucleotide-binding protein subunit alpha.	0.863
B0A48_07592	B0A48_04368	A0A1V8T6I7	A0A1V8TF61	Guanine nucleotide-binding protein alpha-3 subunit.	Uncharacterized protein.	0.822
B0A48_07592	B0A48_08599	A0A1V8T6I7	A0A1V8T6C6	Guanine nucleotide-binding protein alpha-3 subunit.	Uncharacterized protein.	0.822
B0A48_07592	B0A48_13340	A0A1V8T6I7	A0A1V8SPL5	Guanine nucleotide-binding protein alpha-3 subunit.	Uncharacterized protein.	0.639
B0A48_08537	B0A48_04368	A0A1V8T5Z1	A0A1V8TF61	Uncharacterized protein.	Uncharacterized protein.	0.822
B0A48_08537	B0A48_08599	A0A1V8T5Z1	A0A1V8T6C6	Uncharacterized protein.	Uncharacterized protein.	0.822

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

41

average node degree:

7.45

avg. local clustering coefficient:

0.909

expected number of edges:

26

PPI enrichment p-value:

0.00345

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006091

Generation of precursor metabolites and energy

6 of 126

1.06

0.76

0.0060

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051536

Iron-sulfur cluster binding

6 of 75

1.28

1.27

0.00018

GO:0051539

4 iron, 4 sulfur cluster binding

4 of 37

1.41

1.06

0.0032

GO:0005506

Iron ion binding

3 of 24

1.47

0.81

0.0188

GO:0016491

Oxidoreductase activity

7 of 244

0.84

0.63

0.0032

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:471

Tricarboxylic acid cycle, and 4Fe-4S binding domain

5 of 11

2.04

3.17

1.37e-07

CL:467

Mixed, incl. Citrate cycle (TCA cycle), and acetyl-CoA metabolic process

7 of 40

1.62

2.72

1.33e-08

CL:468

Citrate cycle (TCA cycle), and Alpha-helical ferredoxin

6 of 28

1.71

2.69

1.07e-07

CL:462

Mixed, incl. Oxidative phosphorylation, and Carbon metabolism

10 of 118

1.31

2.09

3.19e-10

CL:473

Tricarboxylic acid cycle

2 of 5

1.98

0.94

0.0161

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00620

Pyruvate metabolism

4 of 32

1.47

1.26

0.0010

map00020

Citrate cycle (TCA cycle)

3 of 18

1.6

1.23

0.0020

map01200

Carbon metabolism

5 of 76

1.2

1.03

0.0010

map00650

Butanoate metabolism

2 of 10

1.68

0.89

0.0166

map00190

Oxidative phosphorylation

4 of 70

1.14

0.86

0.0037

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0045272

Plasma membrane respiratory chain complex I

3 of 4

2.25

1.83

0.00033

GOCC:0098803

Respiratory chain complex

4 of 19

1.7

1.58

0.00033

GOCC:1990204

Oxidoreductase complex

4 of 33

1.46

1.28

0.00081

GOCC:1902494

Catalytic complex

5 of 150

0.9

0.64

0.0068

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0249

Electron transport

3 of 15

1.68

1.01

0.0087

KW-0816

Tricarboxylic acid cycle

2 of 7

1.83

0.82

0.0257

KW-0004

4Fe-4S

3 of 29

1.39

0.73

0.0257

KW-0560

Oxidoreductase

4 of 86

1.05

0.6

0.0257

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00037

4Fe-4S binding domain

5 of 6

2.3

3.53

8.60e-08

PF01515

Phosphate acetyl/butaryl transferase

2 of 2

2.38

0.92

0.0204

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR017900

4Fe-4S ferredoxin, iron-sulphur binding, conserved site

6 of 12

2.08

3.54

2.05e-08

IPR017896

4Fe-4S ferredoxin-type, iron-sulphur binding domain

6 of 16

1.95

3.25

4.08e-08

IPR042113

Phosphate acetyltransferase, domain 1

2 of 2

2.38

0.79

0.0356

IPR042112

Phosphate acetyltransferase, domain 2

2 of 2

2.38

0.79

0.0356

IPR002505

Phosphate acetyl/butaryl transferase

2 of 2

2.38

0.79

0.0356

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