B0A48_09095 protein (Rachicladosporium antarcticum)

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

B0A48_09095

Cystathionine beta-lyase. (444 aa)

Predicted Functional Partners:

B0A48_12184

0.940

B0A48_09354

0.940

B0A48_01006

0.929

B0A48_00455

0.929

B0A48_17447

0.928

B0A48_11231

0.928

B0A48_12774

0.925

B0A48_18135

0.924

B0A48_15162

0.910

B0A48_02971

0.910

Your Current Organism:

Rachicladosporium antarcticum

NCBI taxonomy Id: 1507870
Other names: CCFEE 5527, R. antarcticum, Rachicladosporium antarcticum Onofri & Egidi, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A48_00455	B0A48_02971	A0A1V8TUT0	A0A1V8TLS0	Cysteine synthase 1.	Hcy-binding domain-containing protein.	0.833
B0A48_00455	B0A48_09095	A0A1V8TUT0	A0A1V8T1P8	Cysteine synthase 1.	Cystathionine beta-lyase.	0.929
B0A48_00455	B0A48_09354	A0A1V8TUT0	A0A1V8T2Q1	Cysteine synthase 1.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.809
B0A48_00455	B0A48_11231	A0A1V8TUT0	A0A1V8SVC1	Cysteine synthase 1.	Uncharacterized protein.	0.846
B0A48_00455	B0A48_12184	A0A1V8TUT0	A0A1V8STZ5	Cysteine synthase 1.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.810
B0A48_00455	B0A48_12774	A0A1V8TUT0	A0A1V8SRC2	Cysteine synthase 1.	Uncharacterized protein.	0.929
B0A48_00455	B0A48_15162	A0A1V8TUT0	A0A1V8SI52	Cysteine synthase 1.	Hcy-binding domain-containing protein.	0.833
B0A48_00455	B0A48_17447	A0A1V8TUT0	A0A1V8SCS6	Cysteine synthase 1.	Uncharacterized protein.	0.846
B0A48_00455	B0A48_18135	A0A1V8TUT0	A0A1V8SA88	Cysteine synthase 1.	Uncharacterized protein.	0.929
B0A48_01006	B0A48_02971	A0A1V8TS00	A0A1V8TLS0	Cysteine synthase 1.	Hcy-binding domain-containing protein.	0.833
B0A48_01006	B0A48_09095	A0A1V8TS00	A0A1V8T1P8	Cysteine synthase 1.	Cystathionine beta-lyase.	0.929
B0A48_01006	B0A48_09354	A0A1V8TS00	A0A1V8T2Q1	Cysteine synthase 1.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.809
B0A48_01006	B0A48_11231	A0A1V8TS00	A0A1V8SVC1	Cysteine synthase 1.	Uncharacterized protein.	0.846
B0A48_01006	B0A48_12184	A0A1V8TS00	A0A1V8STZ5	Cysteine synthase 1.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.809
B0A48_01006	B0A48_12774	A0A1V8TS00	A0A1V8SRC2	Cysteine synthase 1.	Uncharacterized protein.	0.929
B0A48_01006	B0A48_15162	A0A1V8TS00	A0A1V8SI52	Cysteine synthase 1.	Hcy-binding domain-containing protein.	0.833
B0A48_01006	B0A48_17447	A0A1V8TS00	A0A1V8SCS6	Cysteine synthase 1.	Uncharacterized protein.	0.846
B0A48_01006	B0A48_18135	A0A1V8TS00	A0A1V8SA88	Cysteine synthase 1.	Uncharacterized protein.	0.929
B0A48_02971	B0A48_00455	A0A1V8TLS0	A0A1V8TUT0	Hcy-binding domain-containing protein.	Cysteine synthase 1.	0.833
B0A48_02971	B0A48_01006	A0A1V8TLS0	A0A1V8TS00	Hcy-binding domain-containing protein.	Cysteine synthase 1.	0.833

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.813

expected number of edges:

10

PPI enrichment p-value:

9.29e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003700

DNA-binding transcription factor activity

9 of 102

1.48

2.58

4.68e-10

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6493

LysR, substrate-binding, and Monocarboxylic acid transport

7 of 26

1.96

4.06

1.46e-10

CL:6489

Mixed, incl. LysR, substrate-binding, and SnoaL-like domain

8 of 45

1.78

3.71

4.29e-11

CL:6495

LysR, substrate-binding

6 of 21

1.99

3.64

4.35e-09

CL:6487

Mixed, incl. LysR, substrate-binding, and DNA binding HTH domain, AraC-type

11 of 100

1.57

3.52

8.07e-15

CL:6498

LysR, substrate-binding

5 of 15

2.06

3.21

1.25e-07

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

10 of 1105

0.49

0.35

0.0123

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0805

Transcription regulation

9 of 136

1.35

2.15

1.60e-09

KW-0238

DNA-binding

9 of 170

1.26

1.86

3.66e-09

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03466

LysR substrate binding domain

9 of 29

2.02

5.42

1.23e-14

PF00126

Bacterial regulatory helix-turn-helix protein, lysR family

9 of 30

2.01

5.37

1.23e-14

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005119

LysR, substrate-binding

9 of 29

2.02

5.31

3.10e-14

IPR000847

Transcription regulator HTH, LysR

9 of 31

2.0

5.21

3.10e-14

IPR036390

Winged helix DNA-binding domain superfamily

9 of 101

1.48

2.62

2.84e-10

IPR036388

Winged helix-like DNA-binding domain superfamily

9 of 137

1.35

2.12

2.91e-09

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