B0A48_09349 protein (Rachicladosporium antarcticum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

B0A48_09349

Leukotriene A(4) hydrolase. (639 aa)

Predicted Functional Partners:

B0A48_06168

0.858

B0A48_06083

0.858

B0A48_14964

0.674

B0A48_14589

0.674

B0A48_11176

0.674

B0A48_10661

0.674

B0A48_02243

0.671

B0A48_05683

0.622

B0A48_04574

0.622

B0A48_12262

0.607

Your Current Organism:

Rachicladosporium antarcticum

NCBI taxonomy Id: 1507870
Other names: CCFEE 5527, R. antarcticum, Rachicladosporium antarcticum Onofri & Egidi, 2014

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A48_02243	B0A48_05683	A0A1V8TN18	A0A1V8TBL6	Phosphodiesterase.	Uncharacterized protein.	0.904
B0A48_02243	B0A48_09349	A0A1V8TN18	A0A1V8T2N6	Phosphodiesterase.	Leukotriene A(4) hydrolase.	0.671
B0A48_04574	B0A48_09349	A0A1V8TFQ9	A0A1V8T2N6	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.	Leukotriene A(4) hydrolase.	0.622
B0A48_04574	B0A48_10661	A0A1V8TFQ9	A0A1V8SYG5	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.	Dihydrolipoyl dehydrogenase.	0.444
B0A48_04574	B0A48_11176	A0A1V8TFQ9	A0A1V8SUQ1	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.444
B0A48_04574	B0A48_14589	A0A1V8TFQ9	A0A1V8SL59	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.	Dihydrolipoyl dehydrogenase.	0.444
B0A48_04574	B0A48_14964	A0A1V8TFQ9	A0A1V8SJ41	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.444
B0A48_05683	B0A48_02243	A0A1V8TBL6	A0A1V8TN18	Uncharacterized protein.	Phosphodiesterase.	0.904
B0A48_05683	B0A48_09349	A0A1V8TBL6	A0A1V8T2N6	Uncharacterized protein.	Leukotriene A(4) hydrolase.	0.622
B0A48_05683	B0A48_10661	A0A1V8TBL6	A0A1V8SYG5	Uncharacterized protein.	Dihydrolipoyl dehydrogenase.	0.827
B0A48_05683	B0A48_11176	A0A1V8TBL6	A0A1V8SUQ1	Uncharacterized protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.827
B0A48_05683	B0A48_14589	A0A1V8TBL6	A0A1V8SL59	Uncharacterized protein.	Dihydrolipoyl dehydrogenase.	0.827
B0A48_05683	B0A48_14964	A0A1V8TBL6	A0A1V8SJ41	Uncharacterized protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.827
B0A48_06083	B0A48_06168	A0A1V8TDB4	A0A1V8TAN8	Tryptophan synthase.	Tryptophan synthase.	0.999
B0A48_06083	B0A48_09349	A0A1V8TDB4	A0A1V8T2N6	Tryptophan synthase.	Leukotriene A(4) hydrolase.	0.858
B0A48_06083	B0A48_10661	A0A1V8TDB4	A0A1V8SYG5	Tryptophan synthase.	Dihydrolipoyl dehydrogenase.	0.777
B0A48_06083	B0A48_11176	A0A1V8TDB4	A0A1V8SUQ1	Tryptophan synthase.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.752
B0A48_06083	B0A48_14589	A0A1V8TDB4	A0A1V8SL59	Tryptophan synthase.	Dihydrolipoyl dehydrogenase.	0.777
B0A48_06083	B0A48_14964	A0A1V8TDB4	A0A1V8SJ41	Tryptophan synthase.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.752
B0A48_06168	B0A48_06083	A0A1V8TAN8	A0A1V8TDB4	Tryptophan synthase.	Tryptophan synthase.	0.999

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

27

PPI enrichment p-value:

1.05e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 104

1.5

3.1

6.57e-14

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019843

rRNA binding

10 of 40

1.87

5.09

5.87e-16

GO:0003735

Structural constituent of ribosome

11 of 51

1.81

5.01

2.68e-17

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 57

1.76

4.78

1.76e-17

GO:0044391

Ribosomal subunit

4 of 12

2.0

2.62

2.79e-06

GO:0015934

Large ribosomal subunit

3 of 6

2.17

2.24

4.01e-05

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:34833134

(2021) Genome-Wide Investigation and Analysis of Microsatellites and Compound Microsatellites in Leptolyngbya-like Species, Cyanobacteria.

6 of 15

2.08

4.05

8.68e-10

PMID:32977771

(2020) Role of diversity-generating retroelements for regulatory pathway tuning in cyanobacteria.

2 of 2

2.47

1.47

0.0019

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:151

rRNA-binding

10 of 13

2.36

8.32

1.13e-19

CL:149

rRNA-binding

11 of 21

2.19

7.89

7.79e-21

CL:152

Mixed, incl. Large ribosomal subunit, and K Homology domain, type 2

6 of 7

2.41

5.29

1.63e-11

CL:165

KOW (Kyprides, Ouzounis, Woese) motif., and rRNA-binding

4 of 6

2.3

3.19

4.89e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

cgc03010

Ribosome

11 of 53

1.79

5.02

6.52e-18

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

8 of 39

1.79

3.73

3.88e-11

GOCC:0044391

Ribosomal subunit

6 of 19

1.97

3.67

2.96e-09

GOCC:0022626

Cytosolic ribosome

4 of 16

1.87

2.28

1.04e-05

GOCC:0015934

Large ribosomal subunit

3 of 6

2.17

2.13

6.70e-05

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 13

1.84

1.65

0.00036

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

10 of 39

1.88

5.26

1.55e-16

KW-0689

Ribosomal protein

11 of 57

1.76

4.76

2.68e-17

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About