B0A48_01670 protein (Rachicladosporium antarcticum)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

B0A48_01670

Uncharacterized protein. (469 aa)

Predicted Functional Partners:

B0A48_01163

0.904

B0A48_00354

0.904

B0A48_07009

0.900

B0A48_02612

0.900

B0A48_16318

0.889

B0A48_01993

0.889

B0A48_06220

0.867

B0A48_06027

0.867

B0A48_11299

0.842

B0A48_09029

0.842

Your Current Organism:

Rachicladosporium antarcticum

NCBI taxonomy Id: 1507870
Other names: CCFEE 5527, R. antarcticum, Rachicladosporium antarcticum Onofri & Egidi, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A48_00354	B0A48_01670	A0A1V8TUV2	A0A1V8TQG0	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Uncharacterized protein.	0.904
B0A48_00354	B0A48_01993	A0A1V8TUV2	A0A1V8TRB5	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Uncharacterized protein.	0.915
B0A48_00354	B0A48_02612	A0A1V8TUV2	A0A1V8TPH1	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.428
B0A48_00354	B0A48_07009	A0A1V8TUV2	A0A1V8T811	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.428
B0A48_00354	B0A48_09029	A0A1V8TUV2	A0A1V8T268	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Putative argininosuccinate lyase.	0.486
B0A48_00354	B0A48_11299	A0A1V8TUV2	A0A1V8SV07	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Putative argininosuccinate lyase.	0.486
B0A48_00354	B0A48_16318	A0A1V8TUV2	A0A1V8SFS3	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Uncharacterized protein.	0.915
B0A48_01163	B0A48_01670	A0A1V8TSJ9	A0A1V8TQG0	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Uncharacterized protein.	0.904
B0A48_01163	B0A48_01993	A0A1V8TSJ9	A0A1V8TRB5	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Uncharacterized protein.	0.914
B0A48_01163	B0A48_02612	A0A1V8TSJ9	A0A1V8TPH1	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.428
B0A48_01163	B0A48_07009	A0A1V8TSJ9	A0A1V8T811	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.428
B0A48_01163	B0A48_09029	A0A1V8TSJ9	A0A1V8T268	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Putative argininosuccinate lyase.	0.486
B0A48_01163	B0A48_11299	A0A1V8TSJ9	A0A1V8SV07	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Putative argininosuccinate lyase.	0.486
B0A48_01163	B0A48_16318	A0A1V8TSJ9	A0A1V8SFS3	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	Uncharacterized protein.	0.927
B0A48_01670	B0A48_00354	A0A1V8TQG0	A0A1V8TUV2	Uncharacterized protein.	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	0.904
B0A48_01670	B0A48_01163	A0A1V8TQG0	A0A1V8TSJ9	Uncharacterized protein.	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	0.904
B0A48_01670	B0A48_01993	A0A1V8TQG0	A0A1V8TRB5	Uncharacterized protein.	Uncharacterized protein.	0.889
B0A48_01670	B0A48_02612	A0A1V8TQG0	A0A1V8TPH1	Uncharacterized protein.	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.900
B0A48_01670	B0A48_06027	A0A1V8TQG0	A0A1V8TCN6	Uncharacterized protein.	Uncharacterized protein.	0.867
B0A48_01670	B0A48_06220	A0A1V8TQG0	A0A1V8TAF8	Uncharacterized protein.	Uncharacterized protein.	0.867

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.911

expected number of edges:

10

PPI enrichment p-value:

1.35e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016114

Terpenoid biosynthetic process

8 of 12

2.42

6.7

7.87e-15

GO:0019288

Isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway

7 of 7

2.6

6.7

4.66e-14

GO:0090407

Organophosphate biosynthetic process

8 of 130

1.39

2.15

9.06e-09

GO:0019637

Organophosphate metabolic process

9 of 177

1.3

2.01

1.62e-09

GO:1901135

Carbohydrate derivative metabolic process

9 of 210

1.23

1.77

6.72e-09

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016725

Oxidoreductase activity, acting on CH or CH2 groups

3 of 8

2.17

1.51

0.0013

GO:0051745

4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity

2 of 2

2.6

1.13

0.0086

GO:0051539

4 iron, 4 sulfur cluster binding

3 of 29

1.61

0.99

0.0086

GO:0046872

Metal ion binding

7 of 488

0.75

0.52

0.0086

GO:0043167

Ion binding

9 of 894

0.6

0.43

0.0086

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

5 of 250

0.9

0.53

0.0261

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4282

Isoprenoid biosynthetic process

7 of 11

2.4

5.82

8.50e-13

CL:4281

Isoprenoid metabolic process, and Carotenoid biosynthesis

8 of 21

2.18

5.54

2.10e-13

CL:4284

Isoprene biosynthesis

5 of 5

2.6

4.56

1.70e-09

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00900

Terpenoid backbone biosynthesis

8 of 18

2.24

6.19

1.03e-14

map01110

Biosynthesis of secondary metabolites

9 of 542

0.82

0.78

2.19e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0414

Isoprene biosynthesis

8 of 8

2.6

7.82

1.38e-16

KW-0004

4Fe-4S

3 of 25

1.68

1.22

0.0026

KW-0479

Metal-binding

7 of 228

1.08

1.13

3.48e-05

KW-0560

Oxidoreductase

4 of 118

1.13

0.79

0.0069

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02401

LytB protein

2 of 2

2.6

0.91

0.0220

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