B0A48_00809 protein (Rachicladosporium antarcticum)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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[Homology]

Score

B0A48_00809

Uncharacterized protein. (264 aa)

Predicted Functional Partners:

B0A48_09515

0.991

B0A48_13268

0.990

B0A48_05193

0.990

B0A48_02045

0.990

B0A48_16100

0.989

B0A48_15976

0.989

B0A48_13794

0.989

B0A48_17095

0.988

B0A48_13198

0.988

B0A48_06831

0.983

Your Current Organism:

Rachicladosporium antarcticum

NCBI taxonomy Id: 1507870
Other names: CCFEE 5527, R. antarcticum, Rachicladosporium antarcticum Onofri & Egidi, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A48_00809	B0A48_02045	A0A1V8TRK7	A0A1V8TMH7	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.990
B0A48_00809	B0A48_05193	A0A1V8TRK7	A0A1V8TI67	Uncharacterized protein.	Uncharacterized protein.	0.990
B0A48_00809	B0A48_06831	A0A1V8TRK7	A0A1V8T9X5	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family.	0.983
B0A48_00809	B0A48_09515	A0A1V8TRK7	A0A1V8SXA4	Uncharacterized protein.	Pre-mRNA-splicing factor cwf14.	0.991
B0A48_00809	B0A48_13198	A0A1V8TRK7	A0A1V8SNF9	Uncharacterized protein.	Cir_N domain-containing protein.	0.988
B0A48_00809	B0A48_13268	A0A1V8TRK7	A0A1V8SPC8	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.990
B0A48_00809	B0A48_13794	A0A1V8TRK7	A0A1V8SMP8	Uncharacterized protein.	Pre-mRNA-splicing factor ATP-dependent RNA helicase.	0.989
B0A48_00809	B0A48_15976	A0A1V8TRK7	A0A1V8SG72	Uncharacterized protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.989
B0A48_00809	B0A48_16100	A0A1V8TRK7	A0A1V8SFC4	Uncharacterized protein.	Pre-mRNA-splicing factor ATP-dependent RNA helicase.	0.989
B0A48_00809	B0A48_17095	A0A1V8TRK7	A0A1V8SBK2	Uncharacterized protein.	Cir_N domain-containing protein.	0.988
B0A48_02045	B0A48_00809	A0A1V8TMH7	A0A1V8TRK7	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.990
B0A48_02045	B0A48_05193	A0A1V8TMH7	A0A1V8TI67	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.986
B0A48_02045	B0A48_06831	A0A1V8TMH7	A0A1V8T9X5	WD_REPEATS_REGION domain-containing protein.	Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family.	0.989
B0A48_02045	B0A48_09515	A0A1V8TMH7	A0A1V8SXA4	WD_REPEATS_REGION domain-containing protein.	Pre-mRNA-splicing factor cwf14.	0.991
B0A48_02045	B0A48_13198	A0A1V8TMH7	A0A1V8SNF9	WD_REPEATS_REGION domain-containing protein.	Cir_N domain-containing protein.	0.990
B0A48_02045	B0A48_13794	A0A1V8TMH7	A0A1V8SMP8	WD_REPEATS_REGION domain-containing protein.	Pre-mRNA-splicing factor ATP-dependent RNA helicase.	0.993
B0A48_02045	B0A48_15976	A0A1V8TMH7	A0A1V8SG72	WD_REPEATS_REGION domain-containing protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.999
B0A48_02045	B0A48_16100	A0A1V8TMH7	A0A1V8SFC4	WD_REPEATS_REGION domain-containing protein.	Pre-mRNA-splicing factor ATP-dependent RNA helicase.	0.993
B0A48_02045	B0A48_17095	A0A1V8TMH7	A0A1V8SBK2	WD_REPEATS_REGION domain-containing protein.	Cir_N domain-containing protein.	0.990
B0A48_05193	B0A48_00809	A0A1V8TI67	A0A1V8TRK7	Uncharacterized protein.	Uncharacterized protein.	0.990

page 1 of 6

Network Stats

number of nodes:

4

number of edges:

5

average node degree:

2.5

avg. local clustering coefficient:

0.833

expected number of edges:

3

PPI enrichment p-value:

0.157

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0034614

Cellular response to reactive oxygen species

3 of 47

1.93

1.13

0.0062

GO:0007623

Circadian rhythm

3 of 73

1.74

1.04

0.0081

GO:0048511

Rhythmic process

4 of 147

1.56

1.03

0.0062

GO:0043923

Positive regulation by host of viral transcription

2 of 11

2.38

1.0

0.0143

GO:0070848

Response to growth factor

5 of 252

1.42

0.97

0.0062

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0001221

Transcription coregulator binding

3 of 52

1.88

1.01

0.0107

GO:0061629

RNA polymerase II-specific DNA-binding transcription factor binding

4 of 192

1.44

0.89

0.0107

GO:0004707

MAP kinase activity

2 of 15

2.25

0.86

0.0261

GO:0004402

Histone acetyltransferase activity

2 of 18

2.17

0.83

0.0284

GO:0001223

Transcription coactivator binding

2 of 19

2.14

0.83

0.0284

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005667

Transcription regulator complex

5 of 292

1.36

1.1

0.0018

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7591

Basic region leucin zipper, and CREB phosphorylation

4 of 17

2.49

2.9

3.23e-06

CL:7383

Mixed, incl. Nuclear Receptor transcription pathway, and Basic region leucin zipper

5 of 134

1.69

1.93

3.33e-05

CL:7595

ATF4-CREB1 transcription factor complex, and CREB3 factors activate genes

2 of 5

2.72

1.24

0.0056

CL:7613

PERK regulates gene expression, and Transcription factor AP-1 complex

2 of 6

2.64

1.2

0.0064

CL:6497

Mixed, incl. NGF-stimulated transcription, and Regulation of DNA-templated DNA replication initiation

2 of 6

2.64

1.2

0.0064

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04912

GnRH signaling pathway

3 of 90

1.64

1.02

0.0078

map04916

Melanogenesis

3 of 93

1.63

1.01

0.0078

map04010

MAPK signaling pathway

4 of 307

1.24

0.84

0.0078

map04310

Wnt signaling pathway

3 of 173

1.36

0.83

0.0130

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-198725

Nuclear Events (kinase and transcription factor activation)

5 of 35

2.28

3.5

9.07e-08

MAP-450282

MAPK targets/ Nuclear events mediated by MAP kinases

4 of 28

2.28

2.84

2.58e-06

MAP-187037

Signaling by NTRK1 (TRKA)

5 of 72

1.96

2.71

1.35e-06

MAP-166520

Signaling by NTRKs

5 of 87

1.88

2.54

2.22e-06

MAP-450294

MAP kinase activation

4 of 49

2.03

2.33

1.67e-05

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF09030

Creb binding

2 of 2

3.12

1.25

0.0056

PF02172

KIX domain

2 of 2

3.12

1.25

0.0056

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01250

Histone acetylation protein

2 of 2

3.12

1.54

0.0017

SM00551

TAZ zinc finger, present in p300 and CBP

2 of 2

3.12

1.54

0.0017

SM00338

Basic region leucin zipper

3 of 34

2.07

1.43

0.0017

SM00291

Zinc-binding domain, present in Dystrophin, CREB-binding protein.

2 of 16

2.22

1.0

0.0138

SM00297

Bromo domain

2 of 33

1.9

0.72

0.0428

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