B0A48_00976 protein (Rachicladosporium antarcticum)

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Coexpression

Experiments

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[Homology]

Score

B0A48_00976

Uncharacterized protein. (1121 aa)

Predicted Functional Partners:

B0A48_14873

0.913

B0A48_11083

0.907

B0A48_13892

0.900

B0A48_04888

0.900

B0A48_12933

0.533

B0A48_03992

0.533

B0A48_00689

0.503

B0A48_04267

0.467

B0A48_17007

0.431

B0A48_16560

0.431

Your Current Organism:

Rachicladosporium antarcticum

NCBI taxonomy Id: 1507870
Other names: CCFEE 5527, R. antarcticum, Rachicladosporium antarcticum Onofri & Egidi, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A48_00689	B0A48_00976	A0A1V8TVE2	A0A1V8TRX3	Uncharacterized protein.	Uncharacterized protein.	0.503
B0A48_00976	B0A48_00689	A0A1V8TRX3	A0A1V8TVE2	Uncharacterized protein.	Uncharacterized protein.	0.503
B0A48_00976	B0A48_03992	A0A1V8TRX3	A0A1V8THI6	Uncharacterized protein.	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.	0.533
B0A48_00976	B0A48_04267	A0A1V8TRX3	A0A1V8TFB6	Uncharacterized protein.	BHLH domain-containing protein.	0.467
B0A48_00976	B0A48_04888	A0A1V8TRX3	A0A1V8TDL1	Uncharacterized protein.	Uncharacterized protein.	0.900
B0A48_00976	B0A48_11083	A0A1V8TRX3	A0A1V8SUS0	Uncharacterized protein.	Uncharacterized protein.	0.907
B0A48_00976	B0A48_12933	A0A1V8TRX3	A0A1V8SQS0	Uncharacterized protein.	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.	0.533
B0A48_00976	B0A48_13892	A0A1V8TRX3	A0A1V8SLR3	Uncharacterized protein.	Uncharacterized protein.	0.900
B0A48_00976	B0A48_14873	A0A1V8TRX3	A0A1V8SIQ2	Uncharacterized protein.	Uncharacterized protein.	0.913
B0A48_00976	B0A48_16560	A0A1V8TRX3	A0A1V8SEZ3	Uncharacterized protein.	GP-PDE domain-containing protein.	0.431
B0A48_00976	B0A48_17007	A0A1V8TRX3	A0A1V8SC20	Uncharacterized protein.	Uncharacterized protein.	0.431
B0A48_03992	B0A48_00976	A0A1V8THI6	A0A1V8TRX3	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.	Uncharacterized protein.	0.533
B0A48_03992	B0A48_04888	A0A1V8THI6	A0A1V8TDL1	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.	Uncharacterized protein.	0.909
B0A48_03992	B0A48_11083	A0A1V8THI6	A0A1V8SUS0	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.	Uncharacterized protein.	0.875
B0A48_03992	B0A48_13892	A0A1V8THI6	A0A1V8SLR3	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.	Uncharacterized protein.	0.909
B0A48_03992	B0A48_14873	A0A1V8THI6	A0A1V8SIQ2	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.	Uncharacterized protein.	0.875
B0A48_03992	B0A48_16560	A0A1V8THI6	A0A1V8SEZ3	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.	GP-PDE domain-containing protein.	0.803
B0A48_03992	B0A48_17007	A0A1V8THI6	A0A1V8SC20	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.	Uncharacterized protein.	0.532
B0A48_04267	B0A48_00976	A0A1V8TFB6	A0A1V8TRX3	BHLH domain-containing protein.	Uncharacterized protein.	0.467
B0A48_04888	B0A48_00976	A0A1V8TDL1	A0A1V8TRX3	Uncharacterized protein.	Uncharacterized protein.	0.900

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

68

PPI enrichment p-value:

0.235

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0007165

Signal transduction

11 of 284

1.28

2.11

1.39e-11

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016772

Transferase activity, transferring phosphorus-containing groups

11 of 299

1.26

2.04

1.41e-11

GO:0000155

Phosphorelay sensor kinase activity

5 of 72

1.53

1.68

5.61e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

11 of 872

0.79

0.82

2.86e-07

GO:0016021

Integral component of membrane

11 of 1024

0.72

0.71

5.52e-07

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3585

Signal transduction histidine kinase-related protein, C-terminal

9 of 35

2.1

6.2

2.39e-16

CL:3573

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

10 of 52

1.97

5.85

3.08e-17

CL:3588

Signal transduction histidine kinase-related protein, C-terminal

8 of 30

2.12

5.71

1.69e-14

CL:3563

Signal transduction histidine kinase-related protein, C-terminal

11 of 68

1.9

5.66

3.39e-18

CL:3590

Mixed, incl. Signal transduction histidine kinase, phosphotransfer (Hpt) domain, and Tll0287-like

5 of 16

2.19

3.83

8.91e-09

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02020

Two-component system

11 of 656

0.91

1.06

1.21e-08

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016020

Membrane

11 of 948

0.76

0.75

1.48e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0597

Phosphoprotein

8 of 155

1.4

2.16

1.84e-08

KW-0418

Kinase

4 of 142

1.14

0.71

0.0151

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005467

Histidine kinase domain

9 of 99

1.65

3.3

3.28e-11

IPR036890

Histidine kinase/HSP90-like ATPase superfamily

9 of 114

1.59

3.06

5.49e-11

IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

8 of 92

1.63

3.02

5.54e-10

IPR036097

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily

8 of 93

1.63

3.0

5.54e-10

IPR004358

Signal transduction histidine kinase-related protein, C-terminal

8 of 93

1.63

3.0

5.54e-10

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00387

Histidine kinase-like ATPases

9 of 107

1.62

3.32

4.85e-12

SM00388

His Kinase A (phosphoacceptor) domain

8 of 97

1.61

3.08

1.05e-10

SM00448

cheY-homologous receiver domain

9 of 154

1.46

2.63

5.60e-11

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