B0A48_00081 protein (Rachicladosporium antarcticum)

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

B0A48_00081

Uncharacterized protein. (1148 aa)

Predicted Functional Partners:

B0A48_11880

0.927

B0A48_07531

0.927

B0A48_05683

0.918

B0A48_16971

0.831

B0A48_16412

0.831

B0A48_13455

0.831

B0A48_11015

0.831

B0A48_08692

0.831

B0A48_05030

0.831

B0A48_01767

0.758

Your Current Organism:

Rachicladosporium antarcticum

NCBI taxonomy Id: 1507870
Other names: CCFEE 5527, R. antarcticum, Rachicladosporium antarcticum Onofri & Egidi, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A48_00081	B0A48_01767	A0A1V8TTL5	A0A1V8TIG4	Uncharacterized protein.	Cell division control protein 42.	0.758
B0A48_00081	B0A48_05030	A0A1V8TTL5	A0A1V8TEG1	Uncharacterized protein.	Ras-like protein.	0.831
B0A48_00081	B0A48_05683	A0A1V8TTL5	A0A1V8TBL6	Uncharacterized protein.	Uncharacterized protein.	0.918
B0A48_00081	B0A48_07531	A0A1V8TTL5	A0A1V8T6C9	Uncharacterized protein.	SH3 domain-containing protein.	0.927
B0A48_00081	B0A48_08692	A0A1V8TTL5	A0A1V8T467	Uncharacterized protein.	Uncharacterized protein.	0.831
B0A48_00081	B0A48_11015	A0A1V8TTL5	A0A1V8SZA1	Uncharacterized protein.	Uncharacterized protein.	0.831
B0A48_00081	B0A48_11880	A0A1V8TTL5	A0A1V8ST51	Uncharacterized protein.	SH3 domain-containing protein.	0.927
B0A48_00081	B0A48_13455	A0A1V8TTL5	A0A1V8SQS2	Uncharacterized protein.	Protein ras-2.	0.831
B0A48_00081	B0A48_16412	A0A1V8TTL5	A0A1V8SDV1	Uncharacterized protein.	Ras-like protein.	0.831
B0A48_00081	B0A48_16971	A0A1V8TTL5	A0A1V8SD75	Uncharacterized protein.	Protein ras-2.	0.831
B0A48_01767	B0A48_00081	A0A1V8TIG4	A0A1V8TTL5	Cell division control protein 42.	Uncharacterized protein.	0.758
B0A48_01767	B0A48_05030	A0A1V8TIG4	A0A1V8TEG1	Cell division control protein 42.	Ras-like protein.	0.729
B0A48_01767	B0A48_05683	A0A1V8TIG4	A0A1V8TBL6	Cell division control protein 42.	Uncharacterized protein.	0.999
B0A48_01767	B0A48_07531	A0A1V8TIG4	A0A1V8T6C9	Cell division control protein 42.	SH3 domain-containing protein.	0.603
B0A48_01767	B0A48_08692	A0A1V8TIG4	A0A1V8T467	Cell division control protein 42.	Uncharacterized protein.	0.719
B0A48_01767	B0A48_11015	A0A1V8TIG4	A0A1V8SZA1	Cell division control protein 42.	Uncharacterized protein.	0.719
B0A48_01767	B0A48_11880	A0A1V8TIG4	A0A1V8ST51	Cell division control protein 42.	SH3 domain-containing protein.	0.603
B0A48_01767	B0A48_13455	A0A1V8TIG4	A0A1V8SQS2	Cell division control protein 42.	Protein ras-2.	0.724
B0A48_01767	B0A48_16412	A0A1V8TIG4	A0A1V8SDV1	Cell division control protein 42.	Ras-like protein.	0.729
B0A48_01767	B0A48_16971	A0A1V8TIG4	A0A1V8SD75	Cell division control protein 42.	Protein ras-2.	0.724

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

14

PPI enrichment p-value:

1.11e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003700

DNA-binding transcription factor activity

5 of 81

1.2

0.94

0.0035

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2296

UbiC transcription regulator-associated

3 of 5

2.19

1.65

0.0011

CL:1696

Duplicated hybrid motif, and Glucose permease domain IIB

3 of 12

1.81

1.29

0.0034

CL:1699

Glucose permease domain IIB

2 of 6

1.94

0.89

0.0256

CL:1685

Import into cell, and Hydrolase activity, hydrolyzing O-glycosyl compounds

4 of 120

0.94

0.53

0.0377

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0598

Phosphotransferase system

3 of 27

1.46

1.02

0.0066

KW-0805

Transcription regulation

5 of 96

1.13

0.91

0.0026

KW-0762

Sugar transport

3 of 35

1.35

0.89

0.0107

KW-0238

DNA-binding

5 of 146

0.95

0.69

0.0061

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00367

Phosphotransferase system, EIIB

3 of 12

1.81

1.18

0.0059

PF02378

Phosphotransferase system, EIIC

3 of 24

1.51

0.86

0.0186

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR028978

Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily

4 of 11

1.98

2.01

0.00013

IPR011663

UbiC transcription regulator-associated

4 of 11

1.98

2.01

0.00013

IPR000524

Transcription regulator HTH, GntR

4 of 14

1.87

1.94

0.00013

IPR036878

Glucose permease domain IIB

3 of 12

1.81

1.25

0.0042

IPR018113

Phosphotransferase system EIIB, cysteine phosphorylation site

3 of 12

1.81

1.25

0.0042

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00866

The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to PUBMED:12757941. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules.

4 of 11

1.98

2.46

1.19e-05

SM00345

Helix_turn_helix gluconate operon transcriptional repressor

4 of 14

1.87

2.34

1.33e-05

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