B0A48_00582 protein (Rachicladosporium antarcticum)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

B0A48_00582

Uncharacterized protein. (376 aa)

Predicted Functional Partners:

B0A48_12006

0.710

B0A48_09238

0.710

B0A48_16875

0.674

B0A48_13464

0.674

B0A48_11339

0.674

B0A48_05228

0.674

B0A48_01844

0.674

B0A48_05418

0.534

B0A48_01646

0.534

B0A48_18366

0.528

Your Current Organism:

Rachicladosporium antarcticum

NCBI taxonomy Id: 1507870
Other names: CCFEE 5527, R. antarcticum, Rachicladosporium antarcticum Onofri & Egidi, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A48_00582	B0A48_01646	A0A1V8TV28	A0A1V8TQ94	Uncharacterized protein.	Uncharacterized protein.	0.534
B0A48_00582	B0A48_01844	A0A1V8TV28	A0A1V8TQJ4	Uncharacterized protein.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.674
B0A48_00582	B0A48_05228	A0A1V8TV28	A0A1V8THV5	Uncharacterized protein.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.674
B0A48_00582	B0A48_05418	A0A1V8TV28	A0A1V8TIW7	Uncharacterized protein.	Uncharacterized protein.	0.534
B0A48_00582	B0A48_09238	A0A1V8TV28	A0A1V8T2D4	Uncharacterized protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.710
B0A48_00582	B0A48_11339	A0A1V8TV28	A0A1V8SVJ8	Uncharacterized protein.	FSH1 domain-containing protein.	0.674
B0A48_00582	B0A48_12006	A0A1V8TV28	A0A1V8STU7	Uncharacterized protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.710
B0A48_00582	B0A48_13464	A0A1V8TV28	A0A1V8SNM8	Uncharacterized protein.	FSH1 domain-containing protein.	0.674
B0A48_00582	B0A48_16875	A0A1V8TV28	A0A1V8SE10	Uncharacterized protein.	FSH1 domain-containing protein.	0.674
B0A48_00582	B0A48_18366	A0A1V8TV28	A0A1V8S8C1	Uncharacterized protein.	Uncharacterized protein.	0.528
B0A48_01646	B0A48_00582	A0A1V8TQ94	A0A1V8TV28	Uncharacterized protein.	Uncharacterized protein.	0.534
B0A48_01646	B0A48_05418	A0A1V8TQ94	A0A1V8TIW7	Uncharacterized protein.	Uncharacterized protein.	0.550
B0A48_01646	B0A48_09238	A0A1V8TQ94	A0A1V8T2D4	Uncharacterized protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.763
B0A48_01646	B0A48_12006	A0A1V8TQ94	A0A1V8STU7	Uncharacterized protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.763
B0A48_01844	B0A48_00582	A0A1V8TQJ4	A0A1V8TV28	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Uncharacterized protein.	0.674
B0A48_01844	B0A48_05228	A0A1V8TQJ4	A0A1V8THV5	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.798
B0A48_01844	B0A48_11339	A0A1V8TQJ4	A0A1V8SVJ8	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	FSH1 domain-containing protein.	0.796
B0A48_01844	B0A48_13464	A0A1V8TQJ4	A0A1V8SNM8	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	FSH1 domain-containing protein.	0.796
B0A48_01844	B0A48_16875	A0A1V8TQJ4	A0A1V8SE10	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	FSH1 domain-containing protein.	0.796
B0A48_05228	B0A48_00582	A0A1V8THV5	A0A1V8TV28	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Uncharacterized protein.	0.674

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.886

expected number of edges:

12

PPI enrichment p-value:

2.35e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031929

TOR signaling

4 of 8

2.77

3.41

4.77e-07

GO:0031329

Regulation of cellular catabolic process

5 of 74

1.9

2.4

5.77e-06

GO:0071230

Cellular response to amino acid stimulus

3 of 8

2.64

2.27

6.39e-05

GO:0071038

Nuclear polyadenylation-dependent tRNA catabolic process

3 of 12

2.47

2.16

8.80e-05

GO:0071035

Nuclear polyadenylation-dependent rRNA catabolic process

3 of 12

2.47

2.16

8.80e-05

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0038201

TOR complex

4 of 7

2.82

3.84

7.43e-08

GO:0031932

TORC2 complex

3 of 6

2.77

2.71

1.01e-05

GO:0000176

Nuclear exosome (RNase complex)

3 of 12

2.47

2.33

4.11e-05

GO:1990131

Gtr1-Gtr2 GTPase complex

2 of 2

3.07

1.88

0.00039

GO:0031931

TORC1 complex

2 of 3

2.89

1.78

0.00058

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4006

Mixed, incl. TOR complex, and Gtr1/RagA G protein

7 of 12

2.83

7.61

2.52e-15

CL:4008

Mixed, incl. Gtr1/RagA G protein, and snRNA catabolic process

4 of 6

2.89

4.31

1.06e-08

CL:4020

TORC2 complex

3 of 5

2.85

2.93

4.14e-06

CL:6567

Nuclear polyadenylation-dependent ncRNA catabolic process

2 of 11

2.33

1.15

0.0075

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03018

RNA degradation

3 of 99

1.55

0.92

0.0113

map04136

Autophagy - other

2 of 28

1.92

0.88

0.0211

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-389357

CD28 dependent PI3K/Akt signaling

3 of 6

2.77

2.49

2.66e-05

MAP-6806003

Regulation of TP53 Expression and Degradation

3 of 9

2.59

2.46

2.66e-05

MAP-6804757

Regulation of TP53 Degradation

3 of 9

2.59

2.46

2.66e-05

MAP-5218920

VEGFR2 mediated vascular permeability

3 of 11

2.5

2.44

2.66e-05

MAP-389356

CD28 co-stimulation

3 of 11

2.5

2.44

2.66e-05

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0038201

TOR complex

4 of 8

2.77

3.69

1.36e-07

GOCC:0000178

Exosome (RNase complex)

3 of 13

2.43

2.17

8.24e-05

GOCC:0031931

TORC1 complex

2 of 4

2.77

1.5

0.0019

GOCC:0070209

ASTRA complex

2 of 5

2.67

1.46

0.0022

GOCC:0031932

TORC2 complex

2 of 6

2.59

1.42

0.0025

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR006762

Gtr1/RagA G protein

2 of 2

3.07

1.09

0.0109

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