STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa)    
Predicted Functional Partners:
JMA_23770
Succinate dehydrogenase flavoprotein subunit.
 
 0.992
JMA_23760
Succinate dehydrogenase.
  
 0.972
JMA_12470
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.966
JMA_23780
Succinate dehydrogenase cytochrome B558.
   
 
 0.965
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.954
JMA_24330
NAD-dependent malic enzyme 4.
  
 
 0.941
JMA_36140
Malate dehydrogenase.
  
 
 0.941
mqo
Malate:quinone oxidoreductase.
    
 0.934
glcB
Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
    
 0.932
JMA_24240
Citrate synthase; Belongs to the citrate synthase family.
  
 0.930
Your Current Organism:
Jeotgalibacillus malaysiensis
NCBI taxonomy Id: 1508404
Other names: DSM 28777, J. malaysiensis, Jeotgalibacillus malaysiensis Yaakop et al. 2015, Jeotgalibacillus sp. D5, KCTC 33550, strain D5
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