node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KJY98590.1 | KJY98592.1 | TW72_12740 | TW72_12750 | Cobalamin 5'-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.999 |
KJY98590.1 | KJZ02267.1 | TW72_12740 | TW72_00955 | Cobalamin 5'-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Metallo-beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.674 |
KJY98590.1 | dnaK | TW72_12740 | TW72_07760 | Cobalamin 5'-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.879 |
KJY98590.1 | fdx | TW72_12740 | TW72_12730 | Cobalamin 5'-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.995 |
KJY98590.1 | hscA | TW72_12740 | TW72_12735 | Cobalamin 5'-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chaperone protein HscA; Involved in the maturation of iron-sulfur cluster-containing proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
KJY98590.1 | iscA | TW72_12740 | TW72_12745 | Cobalamin 5'-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |
KJY98590.1 | iscR | TW72_12740 | TW72_12760 | Cobalamin 5'-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.957 |
KJY98590.1 | iscS | TW72_12740 | TW72_12755 | Cobalamin 5'-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.982 |
KJY98590.1 | nfuA | TW72_12740 | TW72_01350 | Cobalamin 5'-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amino acid ABC transporter substrate-binding protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.855 |
KJY98592.1 | KJY98590.1 | TW72_12750 | TW72_12740 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cobalamin 5'-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
KJY98592.1 | KJZ02267.1 | TW72_12750 | TW72_00955 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Metallo-beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |
KJY98592.1 | dnaK | TW72_12750 | TW72_07760 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Molecular chaperone DnaK; Heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.933 |
KJY98592.1 | fdx | TW72_12750 | TW72_12730 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
KJY98592.1 | grxD | TW72_12750 | TW72_17610 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.405 |
KJY98592.1 | hscA | TW72_12750 | TW72_12735 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Chaperone protein HscA; Involved in the maturation of iron-sulfur cluster-containing proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.992 |
KJY98592.1 | iscA | TW72_12750 | TW72_12745 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.977 |
KJY98592.1 | iscR | TW72_12750 | TW72_12760 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.979 |
KJY98592.1 | iscS | TW72_12750 | TW72_12755 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.999 |
KJY98592.1 | nfuA | TW72_12750 | TW72_01350 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Amino acid ABC transporter substrate-binding protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.979 |
KJZ02267.1 | KJY98590.1 | TW72_00955 | TW72_12740 | Metallo-beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin 5'-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.674 |