node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KJY95973.1 | KJY98806.1 | TW72_17830 | TW72_13935 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.987 |
KJY95973.1 | KJY98807.1 | TW72_17830 | TW72_13940 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Branched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.987 |
KJY95973.1 | KJY98809.1 | TW72_17830 | TW72_13950 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.983 |
KJY95973.1 | KJY99829.1 | TW72_17830 | TW72_09375 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.928 |
KJY95973.1 | KJZ00482.1 | TW72_17830 | TW72_07300 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase 3 catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.983 |
KJY95973.1 | ilvH | TW72_17830 | TW72_07305 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase 3 regulatory subunit; With IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.982 |
KJY95973.1 | leuB | TW72_17830 | TW72_17825 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.990 |
KJY95973.1 | leuC | TW72_17830 | TW72_17820 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
KJY95973.1 | leuD | TW72_17830 | TW72_17815 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
KJY95973.1 | sucC | TW72_17830 | TW72_09200 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.928 |
KJY98806.1 | KJY95973.1 | TW72_13935 | TW72_17830 | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.987 |
KJY98806.1 | KJY98807.1 | TW72_13935 | TW72_13940 | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Branched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |
KJY98806.1 | KJY98809.1 | TW72_13935 | TW72_13950 | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.983 |
KJY98806.1 | KJZ00482.1 | TW72_13935 | TW72_07300 | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase 3 catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.940 |
KJY98806.1 | ilvH | TW72_13935 | TW72_07305 | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase 3 regulatory subunit; With IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.915 |
KJY98806.1 | leuB | TW72_13935 | TW72_17825 | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.878 |
KJY98806.1 | leuC | TW72_13935 | TW72_17820 | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
KJY98806.1 | leuD | TW72_13935 | TW72_17815 | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
KJY98807.1 | KJY95973.1 | TW72_13940 | TW72_17830 | Branched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.987 |
KJY98807.1 | KJY98806.1 | TW72_13940 | TW72_13935 | Branched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |