STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemBPorphobilinogen synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ALAD family. (319 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase (hydroxymethylbilane synthase); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.999
CBH21122.1
Uroporphyrinogen III synthase/methyltransferase.
 
 0.999
hemL
Glutamate-1-semialdehyde aminotransferase (aminomutase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.997
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.966
CBH21120.1
Homologs of previously reported genes of unknown function.
 
   
 0.884
cbiF
Cobalt-precorrin-4 C(11)-methyltransferase (Cobalt-precorrin-3 methylase); Belongs to the precorrin methyltransferase family.
 
   
 0.846
cbiH
Cobalt-precorrin-3B C(17)-methyltransferase (Cobalt-precorrin-3 methyltransferase) (Cobalt-precorrin-3 methylase).
     
 0.786
cbiJ
CbiJ protein.
     
 0.773
CBH21114.1
Sirohydrochlorin cobaltochelatase (fragment); Belongs to the precorrin methyltransferase family.
     
 0.772
cobD
Cobalamin biosynthesis protein cobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
     
 0.762
Your Current Organism:
Acetoanaerobium sticklandii
NCBI taxonomy Id: 1511
Other names: A. sticklandii, ATCC 12662, BCRC 14485, CCRC 14485, CCRC:14485, CCUG 9281, Clostridium sticklandii, DSM 519, NCIMB 10654, strain StadtmanHF
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