node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBH21099.1 | CBH22040.1 | CLOST_0976 | CLOST_1920 | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. | Homologs of previously reported genes of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.931 |
CBH21099.1 | cobB | CLOST_0976 | CLOST_0981 | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.960 |
CBH21099.1 | cobD | CLOST_0976 | CLOST_0982 | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. | Cobalamin biosynthesis protein cobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.964 |
CBH21099.1 | cobQ | CLOST_0976 | CLOST_0955 | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.991 |
CBH21099.1 | cobS | CLOST_0976 | CLOST_1102 | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.970 |
CBH21099.1 | cobT | CLOST_0976 | CLOST_0282 | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. | Nicotinate-nucleotide dimethylbenzimidazole-P phophoribosyl transferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.641 |
CBH21099.1 | cobU | CLOST_0976 | CLOST_1101 | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. | Bifunctional cobinamide kinase and cobinamide phosphate guanylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.974 |
CBH21222.1 | CBH21225.1 | CLOST_1100 | CLOST_1103 | Putative exported protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative cobalamin biosynthesis phosphoglycerate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.800 |
CBH21222.1 | cobS | CLOST_1100 | CLOST_1102 | Putative exported protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.787 |
CBH21222.1 | cobU | CLOST_1100 | CLOST_1101 | Putative exported protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Bifunctional cobinamide kinase and cobinamide phosphate guanylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.787 |
CBH21225.1 | CBH21222.1 | CLOST_1103 | CLOST_1100 | Putative cobalamin biosynthesis phosphoglycerate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative exported protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.800 |
CBH21225.1 | cobQ | CLOST_1103 | CLOST_0955 | Putative cobalamin biosynthesis phosphoglycerate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.605 |
CBH21225.1 | cobS | CLOST_1103 | CLOST_1102 | Putative cobalamin biosynthesis phosphoglycerate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.993 |
CBH21225.1 | cobT | CLOST_1103 | CLOST_0282 | Putative cobalamin biosynthesis phosphoglycerate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Nicotinate-nucleotide dimethylbenzimidazole-P phophoribosyl transferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.961 |
CBH21225.1 | cobU | CLOST_1103 | CLOST_1101 | Putative cobalamin biosynthesis phosphoglycerate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Bifunctional cobinamide kinase and cobinamide phosphate guanylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.897 |
CBH22040.1 | CBH21099.1 | CLOST_1920 | CLOST_0976 | Homologs of previously reported genes of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. | 0.931 |
CBH22040.1 | cobB | CLOST_1920 | CLOST_0981 | Homologs of previously reported genes of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.916 |
CBH22040.1 | cobD | CLOST_1920 | CLOST_0982 | Homologs of previously reported genes of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin biosynthesis protein cobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.916 |
CBH22040.1 | cobQ | CLOST_1920 | CLOST_0955 | Homologs of previously reported genes of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.917 |
CBH22040.1 | cobS | CLOST_1920 | CLOST_1102 | Homologs of previously reported genes of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.921 |