node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBH21419.1 | CBH21422.1 | CLOST_1299 | CLOST_1302 | Positive regulator of sigma E, RseC/MucC. | Putative coproporphyrinogen III oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.705 |
CBH21419.1 | CBH21423.1 | CLOST_1299 | CLOST_1303 | Positive regulator of sigma E, RseC/MucC. | Beta-lactamase domain protein. | 0.691 |
CBH21419.1 | aspS-2 | CLOST_1299 | CLOST_1300 | Positive regulator of sigma E, RseC/MucC. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.752 |
CBH21419.1 | dtd | CLOST_1299 | CLOST_1304 | Positive regulator of sigma E, RseC/MucC. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.701 |
CBH21419.1 | hisS-2 | CLOST_1299 | CLOST_1301 | Positive regulator of sigma E, RseC/MucC. | Histidyl tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.698 |
CBH21419.1 | relA | CLOST_1299 | CLOST_1305 | Positive regulator of sigma E, RseC/MucC. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.696 |
CBH21419.1 | rnfB | CLOST_1299 | CLOST_1397 | Positive regulator of sigma E, RseC/MucC. | Electron transport complex, RnfABCDGE type, B subunit precursor; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. | 0.780 |
CBH21419.1 | rnfC | CLOST_1299 | CLOST_1402 | Positive regulator of sigma E, RseC/MucC. | Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | 0.669 |
CBH21419.1 | rnfD | CLOST_1299 | CLOST_1401 | Positive regulator of sigma E, RseC/MucC. | Putative inner membrane oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. | 0.651 |
CBH21419.1 | rnfG | CLOST_1299 | CLOST_1400 | Positive regulator of sigma E, RseC/MucC. | Electron transport complex protein precursor; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. | 0.699 |
CBH21422.1 | CBH21419.1 | CLOST_1302 | CLOST_1299 | Putative coproporphyrinogen III oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Positive regulator of sigma E, RseC/MucC. | 0.705 |
CBH21422.1 | CBH21423.1 | CLOST_1302 | CLOST_1303 | Putative coproporphyrinogen III oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Beta-lactamase domain protein. | 0.854 |
CBH21422.1 | aspS-2 | CLOST_1302 | CLOST_1300 | Putative coproporphyrinogen III oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.736 |
CBH21422.1 | dtd | CLOST_1302 | CLOST_1304 | Putative coproporphyrinogen III oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.800 |
CBH21422.1 | hisS-2 | CLOST_1302 | CLOST_1301 | Putative coproporphyrinogen III oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Histidyl tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.847 |
CBH21422.1 | relA | CLOST_1302 | CLOST_1305 | Putative coproporphyrinogen III oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.793 |
CBH21423.1 | CBH21419.1 | CLOST_1303 | CLOST_1299 | Beta-lactamase domain protein. | Positive regulator of sigma E, RseC/MucC. | 0.691 |
CBH21423.1 | CBH21422.1 | CLOST_1303 | CLOST_1302 | Beta-lactamase domain protein. | Putative coproporphyrinogen III oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.854 |
CBH21423.1 | aspS-2 | CLOST_1303 | CLOST_1300 | Beta-lactamase domain protein. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.736 |
CBH21423.1 | dtd | CLOST_1303 | CLOST_1304 | Beta-lactamase domain protein. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.848 |