STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadCQuinolinate phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NadC/ModD family. (265 aa)    
Predicted Functional Partners:
nadB
Quinolinate synthase, L-aspartate oxidase (B protein) subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.999
nadA
Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 0.999
yueK
YueK; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
   
 0.967
nadD
Nicotinic acid mononucleotide adenylyltransferase, NAD(P)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.943
SurE
Predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.902
CBH20411.1
5'-Nucleotidase domain protein precursor; Belongs to the 5'-nucleotidase family.
    
  0.900
CBH21922.1
Protein of unknown function; No homology to any previously reported sequences.
       0.752
CBH22596.1
NUDIX hydrolase.
 
    0.656
purD
Phosphoribosylamine--glycine ligase (modular protein); Belongs to the GARS family.
  
  
 0.650
ribD
Fused diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.636
Your Current Organism:
Acetoanaerobium sticklandii
NCBI taxonomy Id: 1511
Other names: A. sticklandii, ATCC 12662, BCRC 14485, CCRC 14485, CCRC:14485, CCUG 9281, Clostridium sticklandii, DSM 519, NCIMB 10654, strain StadtmanHF
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.