STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBH22040.1Homologs of previously reported genes of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family. (182 aa)    
Predicted Functional Partners:
CBH21099.1
ATP:corrinoid adenosyltransferase BtuR/CobO/CobP.
    
 0.931
cobU
Bifunctional cobinamide kinase and cobinamide phosphate guanylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.921
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
    
 0.921
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 
 0.917
cobB
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
    
 0.916
cobD
Cobalamin biosynthesis protein cobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
    
 0.916
eutT
Putative cobalamin adenosyltransferase in ethanolamine utilization; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.914
CBH20274.1
Putative 5-methyltetrahydrofolate--homocysteine methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
   
 0.695
CBH21122.1
Uroporphyrinogen III synthase/methyltransferase.
 
  
 0.647
CBH22375.1
Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent.
 
   
 0.636
Your Current Organism:
Acetoanaerobium sticklandii
NCBI taxonomy Id: 1511
Other names: A. sticklandii, ATCC 12662, BCRC 14485, CCRC 14485, CCRC:14485, CCUG 9281, Clostridium sticklandii, DSM 519, NCIMB 10654, strain StadtmanHF
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