STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hsdMType I restriction modification system protein HsdMI. (515 aa)    
Predicted Functional Partners:
CBH22089.1
Restriction modification system DNA specificity domain.
 
 0.998
hsdR
Putative Type I site-specific deoxyribonuclease; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 0.997
CBH21384.1
Restriction modification system DNA specificity domain.
 
 
 0.946
CBH21382.1
Type III restriction protein res subunit.
  
 
 0.784
CBH21157.1
Predicted type II restriction enzyme, methylase subunit.
  
    0.465
uvrB
Excinulease of nucleotide excision repair, DNA damage recognition component; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. I [...]
    
 
 0.454
CBH21156.1
Homologs of previously reported genes of unknown function.
  
    0.452
CBH21161.1
Homologs of previously reported genes of unknown function.
  
    0.430
CBH22450.1
Protein of unknown function; No homology to any previously reported sequences.
    
   0.429
yloA
Putative fibronectin binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.401
Your Current Organism:
Acetoanaerobium sticklandii
NCBI taxonomy Id: 1511
Other names: A. sticklandii, ATCC 12662, BCRC 14485, CCRC 14485, CCRC:14485, CCUG 9281, Clostridium sticklandii, DSM 519, NCIMB 10654, strain StadtmanHF
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