| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBH20175.1 | orr | CLOST_0045 | CLOST_1288 | Alanine racemase domain protein. | Ornithine racemase; Involved in the ornithine fermentation pathway. Catalyzes the conversion of L-ornithine to D-ornithine. OR could also racemize basic amino acids such as lysine and arginine. Serine, asparagine and alanine could be also converted by OR, but at a lower rate. | 0.907 |
| CBH20175.1 | proC | CLOST_0045 | CLOST_1972 | Alanine racemase domain protein. | Pyrroline-5-carboxylate reductase, NAD(P)-binding; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.800 |
| CBH21163.1 | prdF | CLOST_1040 | CLOST_2228 | Homologs of previously reported genes of unknown function. | Proline racemase A precursor (TcPRACA) (TcPA45-A) (rTcPA45); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the proline racemase family. | 0.900 |
| CBH21163.1 | proC | CLOST_1040 | CLOST_1972 | Homologs of previously reported genes of unknown function. | Pyrroline-5-carboxylate reductase, NAD(P)-binding; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.900 |
| astC | guaA | CLOST_0136 | CLOST_0297 | Succinylornithine transaminase, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.634 |
| astC | proC | CLOST_0136 | CLOST_1972 | Succinylornithine transaminase, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Pyrroline-5-carboxylate reductase, NAD(P)-binding; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.544 |
| astC | purD | CLOST_0136 | CLOST_0339 | Succinylornithine transaminase, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Phosphoribosylamine--glycine ligase (modular protein); Belongs to the GARS family. | 0.608 |
| guaA | astC | CLOST_0297 | CLOST_0136 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Succinylornithine transaminase, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.634 |
| guaA | pheA | CLOST_0297 | CLOST_0652 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | PheA. | 0.693 |
| guaA | proC | CLOST_0297 | CLOST_1972 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Pyrroline-5-carboxylate reductase, NAD(P)-binding; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.634 |
| guaA | purD | CLOST_0297 | CLOST_0339 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylamine--glycine ligase (modular protein); Belongs to the GARS family. | 0.997 |
| guaA | ribD | CLOST_0297 | CLOST_0410 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Fused diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.647 |
| orr | CBH20175.1 | CLOST_1288 | CLOST_0045 | Ornithine racemase; Involved in the ornithine fermentation pathway. Catalyzes the conversion of L-ornithine to D-ornithine. OR could also racemize basic amino acids such as lysine and arginine. Serine, asparagine and alanine could be also converted by OR, but at a lower rate. | Alanine racemase domain protein. | 0.907 |
| orr | proC | CLOST_1288 | CLOST_1972 | Ornithine racemase; Involved in the ornithine fermentation pathway. Catalyzes the conversion of L-ornithine to D-ornithine. OR could also racemize basic amino acids such as lysine and arginine. Serine, asparagine and alanine could be also converted by OR, but at a lower rate. | Pyrroline-5-carboxylate reductase, NAD(P)-binding; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.800 |
| pheA | guaA | CLOST_0652 | CLOST_0297 | PheA. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.693 |
| pheA | proC | CLOST_0652 | CLOST_1972 | PheA. | Pyrroline-5-carboxylate reductase, NAD(P)-binding; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.512 |
| pheA | purD | CLOST_0652 | CLOST_0339 | PheA. | Phosphoribosylamine--glycine ligase (modular protein); Belongs to the GARS family. | 0.666 |
| prdF | CBH21163.1 | CLOST_2228 | CLOST_1040 | Proline racemase A precursor (TcPRACA) (TcPA45-A) (rTcPA45); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the proline racemase family. | Homologs of previously reported genes of unknown function. | 0.900 |
| prdF | proC | CLOST_2228 | CLOST_1972 | Proline racemase A precursor (TcPRACA) (TcPA45-A) (rTcPA45); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the proline racemase family. | Pyrroline-5-carboxylate reductase, NAD(P)-binding; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.915 |
| proC | CBH20175.1 | CLOST_1972 | CLOST_0045 | Pyrroline-5-carboxylate reductase, NAD(P)-binding; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Alanine racemase domain protein. | 0.800 |