STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBH22425.1Protein of unknown function; No homology to any previously reported sequences. (847 aa)    
Predicted Functional Partners:
scpA
ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.819
CBH22424.1
Homologs of previously reported genes of unknown function.
       0.794
hag
Hag; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
   
   0.658
gyrB
DNA gyrase (subunit B); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.580
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.551
CBH22426.1
Homologs of previously reported genes of unknown function.
       0.519
CBH22422.1
Putative Flagellar protein FliS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.504
CBH22350.1
Putative uncharacterized protein (PrdD); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
 
 0.464
CBH21376.1
Homologs of previously reported genes of unknown function.
  
 
 0.434
yhgF
Transcriptional accessory protein; Function of strongly homologous gene; factor.
  
    0.426
Your Current Organism:
Acetoanaerobium sticklandii
NCBI taxonomy Id: 1511
Other names: A. sticklandii, ATCC 12662, BCRC 14485, CCRC 14485, CCRC:14485, CCUG 9281, Clostridium sticklandii, DSM 519, NCIMB 10654, strain StadtmanHF
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