STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CBH22523.1Putative peroxiredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (240 aa)    
Predicted Functional Partners:
CBH21558.1
FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.939
trxB
Thioredoxin reductase.
  
 
 0.732
CBH20876.1
Homologs of previously reported genes of unknown function.
  
 0.656
CBH21918.1
Exported protein of unknown function; No homology to any previously reported sequences.
  
 0.656
CBH20888.1
Redox-active disulfide protein 2.
  
 0.641
CBH22070.1
Pyridine nucleotide-disulphide oxidoreductase family protein.
  
 
 0.641
CBH22033.1
Homologs of previously reported genes of unknown function.
  
  
 0.572
CBH20286.1
General stress protein 20U; Belongs to the Dps family.
  
  
 0.558
CBH22200.1
Ferritin; Iron-storage protein.
  
  
 0.533
grpE
GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interacti [...]
   
 
 0.530
Your Current Organism:
Acetoanaerobium sticklandii
NCBI taxonomy Id: 1511
Other names: A. sticklandii, ATCC 12662, BCRC 14485, CCRC 14485, CCRC:14485, CCUG 9281, Clostridium sticklandii, DSM 519, NCIMB 10654, strain StadtmanHF
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