STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E7GLR0_CLOSYUnannotated protein. (513 aa)    
Predicted Functional Partners:
E7GLR1_CLOSY
Unannotated protein.
 
 0.951
E7GLV9_CLOSY
Unannotated protein; Belongs to the UPF0102 family.
 
  
 0.822
topA
Unannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.735
E7GQZ2_CLOSY
Unannotated protein.
 
  
 0.711
codY
Unannotated protein; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
       0.578
E7GPU8_CLOSY
Unannotated protein.
 
   
 0.567
E7GJ53_CLOSY
Unannotated protein.
 
  
 0.427
E7GGR5_CLOSY
Unannotated protein.
 
     0.420
def-2
Unannotated protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
 
     0.411
E7GUE1_CLOSY
Unannotated protein.
  
  
 0.410
Your Current Organism:
Clostridium symbiosum
NCBI taxonomy Id: 1512
Other names: ATCC 14940, Bacteroides symbiosus, DSM 934, [. symbiosum, [Clostridium] symbiosum
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