STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E7GLR1_CLOSYUnannotated protein. (390 aa)    
Predicted Functional Partners:
E7GLR0_CLOSY
Unannotated protein.
 
 0.951
topA
Unannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.925
E7GQZ2_CLOSY
Unannotated protein.
 
 
 0.918
E7GJ53_CLOSY
Unannotated protein.
 
  
 0.824
E7GR90_CLOSY
Unannotated protein.
  
  
 0.756
E7GSK5_CLOSY
Unannotated protein.
  
    0.725
E7GTH3_CLOSY
Unannotated protein.
   
    0.713
E7GLV9_CLOSY
Unannotated protein; Belongs to the UPF0102 family.
 
    0.701
E7GUD4_CLOSY
Unannotated protein.
 
   
 0.689
E7GSV5_CLOSY
Unannotated protein; Belongs to the UPF0758 family.
  
  
 0.687
Your Current Organism:
Clostridium symbiosum
NCBI taxonomy Id: 1512
Other names: ATCC 14940, Bacteroides symbiosus, DSM 934, [. symbiosum, [Clostridium] symbiosum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.