KPB01504.1 protein (Ahrensia marina) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

KPB01504.1

Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (368 aa)

Predicted Functional Partners:

KPB02764.1

0.874

KPB02765.1

0.839

KPB01035.1

0.820

KPB01034.1

0.815

KPB00045.1

0.806

KPB02520.1

0.804

KPB01099.1

0.804

KPB00515.1

0.804

KPB00044.1

0.804

KPB01982.1

0.796

Your Current Organism:

Ahrensia marina

NCBI taxonomy Id: 1514904
Other names: A. marina, Ahrensia marina Liu et al. 2016, Ahrensia sp. LZD062, DSM 28886, JCM 30117, MCCC 1K00254, strain LZD062

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KPB00044.1	KPB00045.1	SU32_15845	SU32_15850	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
KPB00044.1	KPB01034.1	SU32_15845	SU32_10325	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
KPB00044.1	KPB01035.1	SU32_15845	SU32_10335	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Spermidine/putrescine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.855
KPB00044.1	KPB01504.1	SU32_15845	SU32_07945	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.804
KPB00045.1	KPB00044.1	SU32_15850	SU32_15845	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
KPB00045.1	KPB00515.1	SU32_15850	SU32_13590	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994
KPB00045.1	KPB01034.1	SU32_15850	SU32_10325	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.663
KPB00045.1	KPB01035.1	SU32_15850	SU32_10335	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Spermidine/putrescine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.864
KPB00045.1	KPB01099.1	SU32_15850	SU32_10330	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.993
KPB00045.1	KPB01504.1	SU32_15850	SU32_07945	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.806
KPB00045.1	KPB02520.1	SU32_15850	SU32_01845	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Putrescine/spermidine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
KPB00515.1	KPB00045.1	SU32_13590	SU32_15850	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994
KPB00515.1	KPB01034.1	SU32_13590	SU32_10325	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.992
KPB00515.1	KPB01035.1	SU32_13590	SU32_10335	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Spermidine/putrescine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.855
KPB00515.1	KPB01504.1	SU32_13590	SU32_07945	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.804
KPB01034.1	KPB00044.1	SU32_10325	SU32_15845	Polyamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
KPB01034.1	KPB00045.1	SU32_10325	SU32_15850	Polyamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.663
KPB01034.1	KPB00515.1	SU32_10325	SU32_13590	Polyamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.992
KPB01034.1	KPB01035.1	SU32_10325	SU32_10335	Polyamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Spermidine/putrescine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994
KPB01034.1	KPB01099.1	SU32_10325	SU32_10330	Polyamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997

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Network Stats

number of nodes:

11

number of edges:

15

average node degree:

2.73

avg. local clustering coefficient:

0.843

expected number of edges:

11

PPI enrichment p-value:

0.121

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006779

Porphyrin-containing compound biosynthetic process

7 of 52

1.79

3.16

8.27e-09

GO:0006782

Protoporphyrinogen IX biosynthetic process

6 of 48

1.76

2.76

1.27e-07

GO:0019438

Aromatic compound biosynthetic process

8 of 279

1.12

1.33

1.47e-06

GO:0018130

Heterocycle biosynthetic process

8 of 302

1.09

1.25

2.50e-06

GO:1901362

Organic cyclic compound biosynthetic process

8 of 314

1.07

1.21

3.14e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004853

Uroporphyrinogen decarboxylase activity

5 of 43

1.73

2.04

1.99e-05

GO:0003824

Catalytic activity

11 of 2412

0.32

0.24

0.0425

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1549

0.47

0.35

0.0078

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2741

Mixed, incl. TGS domain, and Anaerobic coproporphyrinogen-III oxidase

4 of 5

2.57

3.07

1.64e-06

CL:5777

Uroporphyrinogen decarboxylase (URO-D), and Methionine synthase domain

5 of 51

1.66

1.9

3.11e-05

CL:5778

Uroporphyrinogen decarboxylase (URO-D), and Methionine synthase domain

4 of 46

1.6

1.46

0.00047

CL:5844

Mixed, incl. Methyltransferase MtaA/CmuA, and Methyltransferase complex

2 of 13

1.85

0.75

0.0372

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00860

Porphyrin and chlorophyll metabolism

5 of 108

1.33

1.29

0.00026

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01208

Uroporphyrinogen decarboxylase (URO-D)

5 of 41

1.75

2.1

1.49e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000257

Uroporphyrinogen decarboxylase (URO-D)

5 of 41

1.75

1.96

3.86e-05

IPR038071

UROD/MetE-like superfamily

5 of 47

1.69

1.9

3.86e-05

IPR034505

Anaerobic coproporphyrinogen-III oxidase

2 of 2

2.66

1.0

0.0152

IPR006360

Methyltransferase MtaA/CmuA

2 of 2

2.66

1.0

0.0152

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