API5 protein (Eumeta japonica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

API5

Apoptosis inhibitor 5. (602 aa)

Predicted Functional Partners:

rpoB

0.860

rpoB-2

0.860

RpII140

0.860

RpII140-2

0.860

rpoC

0.849

DHX15

0.581

Cherp

0.574

Abce1

0.559

ddx42

0.470

Nlp

0.470

Your Current Organism:

Eumeta japonica

NCBI taxonomy Id: 151549
Other names: E. japonica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
API5	Abce1	A0A4C1SS14	A0A4C1XEE4	Apoptosis inhibitor 5.	ATP-binding cassette sub-family E member 1.	0.559
API5	Cherp	A0A4C1SS14	A0A4C1XH76	Apoptosis inhibitor 5.	Calcium homeostasis endoplasmic reticulum protein.	0.574
API5	DHX15	A0A4C1SS14	A0A4C1Y1Q3	Apoptosis inhibitor 5.	Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15.	0.581
API5	Nlp	A0A4C1SS14	A0A4C1UR56	Apoptosis inhibitor 5.	Nucleoplasmin-like protein.	0.470
API5	RpII140	A0A4C1SS14	A0A4C1T978	Apoptosis inhibitor 5.	DNA-directed RNA polymerase II subunit RPB2.	0.860
API5	RpII140-2	A0A4C1SS14	A0A4C1XIT7	Apoptosis inhibitor 5.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.860
API5	ddx42	A0A4C1SS14	A0A4C1TQ22	Apoptosis inhibitor 5.	ATP-dependent RNA helicase DDX42.	0.470
API5	rpoB	A0A4C1SS14	A0A4C1SJB0	Apoptosis inhibitor 5.	DNA-directed RNA polymerase subunit beta.	0.860
API5	rpoB-2	A0A4C1SS14	A0A4C1SM81	Apoptosis inhibitor 5.	DNA-directed RNA polymerase subunit beta; Belongs to the RNA polymerase beta chain family.	0.860
API5	rpoC	A0A4C1SS14	A0A4C1SK25	Apoptosis inhibitor 5.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.849
Abce1	API5	A0A4C1XEE4	A0A4C1SS14	ATP-binding cassette sub-family E member 1.	Apoptosis inhibitor 5.	0.559
Abce1	DHX15	A0A4C1XEE4	A0A4C1Y1Q3	ATP-binding cassette sub-family E member 1.	Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15.	0.895
Abce1	RpII140	A0A4C1XEE4	A0A4C1T978	ATP-binding cassette sub-family E member 1.	DNA-directed RNA polymerase II subunit RPB2.	0.444
Abce1	RpII140-2	A0A4C1XEE4	A0A4C1XIT7	ATP-binding cassette sub-family E member 1.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.444
Abce1	rpoB	A0A4C1XEE4	A0A4C1SJB0	ATP-binding cassette sub-family E member 1.	DNA-directed RNA polymerase subunit beta.	0.444
Abce1	rpoB-2	A0A4C1XEE4	A0A4C1SM81	ATP-binding cassette sub-family E member 1.	DNA-directed RNA polymerase subunit beta; Belongs to the RNA polymerase beta chain family.	0.444
Abce1	rpoC	A0A4C1XEE4	A0A4C1SK25	ATP-binding cassette sub-family E member 1.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.444
Cherp	API5	A0A4C1XH76	A0A4C1SS14	Calcium homeostasis endoplasmic reticulum protein.	Apoptosis inhibitor 5.	0.574
Cherp	DHX15	A0A4C1XH76	A0A4C1Y1Q3	Calcium homeostasis endoplasmic reticulum protein.	Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15.	0.997
Cherp	ddx42	A0A4C1XH76	A0A4C1TQ22	Calcium homeostasis endoplasmic reticulum protein.	ATP-dependent RNA helicase DDX42.	0.976