node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HR45_02370 | HR45_03760 | HR45_02370 | HR45_03760 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.654 |
HR45_02370 | HR45_03770 | HR45_02370 | HR45_03770 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.447 |
HR45_02370 | yihI | HR45_02370 | HR45_17165 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminotransferase; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.497 |
HR45_02720 | HR45_03760 | HR45_02720 | HR45_03760 | N-carbamyl-L-amino acid amidohydrolase; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.686 |
HR45_02720 | HR45_03765 | HR45_02720 | HR45_03765 | N-carbamyl-L-amino acid amidohydrolase; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0352 family. | 0.774 |
HR45_02720 | HR45_03770 | HR45_02720 | HR45_03770 | N-carbamyl-L-amino acid amidohydrolase; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Sulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.543 |
HR45_02720 | HR45_05455 | HR45_02720 | HR45_05455 | N-carbamyl-L-amino acid amidohydrolase; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.757 |
HR45_02720 | HR45_10830 | HR45_02720 | HR45_10830 | N-carbamyl-L-amino acid amidohydrolase; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.448 |
HR45_02720 | rraB | HR45_02720 | HR45_14520 | N-carbamyl-L-amino acid amidohydrolase; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Regulator; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.767 |
HR45_02720 | syd | HR45_02720 | HR45_12380 | N-carbamyl-L-amino acid amidohydrolase; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Protein syd; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. | 0.731 |
HR45_02720 | yihI | HR45_02720 | HR45_17165 | N-carbamyl-L-amino acid amidohydrolase; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Aminotransferase; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.772 |
HR45_03760 | HR45_02370 | HR45_03760 | HR45_02370 | Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.654 |
HR45_03760 | HR45_02720 | HR45_03760 | HR45_02720 | Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-carbamyl-L-amino acid amidohydrolase; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | 0.686 |
HR45_03760 | HR45_03765 | HR45_03760 | HR45_03765 | Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0352 family. | 0.824 |
HR45_03760 | HR45_03770 | HR45_03760 | HR45_03770 | Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.821 |
HR45_03760 | HR45_05455 | HR45_03760 | HR45_05455 | Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.634 |
HR45_03760 | HR45_10830 | HR45_03760 | HR45_10830 | Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.556 |
HR45_03760 | rlmM | HR45_03760 | HR45_07100 | Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 23S rRNA methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.599 |
HR45_03760 | rraB | HR45_03760 | HR45_14520 | Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Regulator; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.523 |
HR45_03760 | syd | HR45_03760 | HR45_12380 | Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein syd; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. | 0.518 |