Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arlSSignal transduction histidine kinase. (456 aa)    
Predicted Functional Partners:
arlR
Response regulator.
 
 0.996
AND84693.1
DNA-binding response regulator.
 
 
 0.813
mprA
Response regulator.
 
 
 0.813
phoP_1
Response regulator.
 
 
 0.806
srrA_4
Response regulator.
 
 
 0.801
AND84744.1
Hypothetical protein.
 
 
 0.800
srrA_3
Transcriptional regulator.
 
 
 0.799
srrA_2
Hypothetical protein.
 
   0.784
vanR
Regulatory protein VanR.
 
   0.768
AND84702.1
Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain.
 
   0.768
Your Current Organism:
Clostridium tyrobutyricum
NCBI taxonomy Id: 1519
Other names: ATCC 25755, C. tyrobutyricum, CCUG 48315, CIP 105092, Clostridium sp. GPRE 4-2, DSM 2637, JCM 11008
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