spoIIAA protein (Clostridium tyrobutyricum) - STRING interaction network

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Score

spoIIAA

Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. (111 aa)

Predicted Functional Partners:

spoIIAB

0.997

sigF

0.974

spoIIE

0.842

sigG

0.817

spoIIGA

0.807

spoIIP

0.804

spoIIR

0.800

spoIIID

0.790

spoIVA

0.784

spo0A

0.736

Your Current Organism:

Clostridium tyrobutyricum

NCBI taxonomy Id: 1519
Other names: ATCC 25755, C. tyrobutyricum, CCUG 48315, CIP 105092, Clostridium sp. GPRE 4-2, DSM 2637, JCM 11008

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
sigF	spo0A	CTK_C08860	CTK_C19430	RNA polymerase sigma factor; Belongs to the sigma-70 factor family.	Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	0.831
sigF	spoIIAA	CTK_C08860	CTK_C08840	RNA polymerase sigma factor; Belongs to the sigma-70 factor family.	Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.	0.974
sigF	spoIIAB	CTK_C08860	CTK_C08850	RNA polymerase sigma factor; Belongs to the sigma-70 factor family.	Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.990
sigF	spoIIE	CTK_C08860	CTK_C29350	RNA polymerase sigma factor; Belongs to the sigma-70 factor family.	Stage II sporulation protein E.	0.849
sigF	spoIIGA	CTK_C08860	CTK_C18750	RNA polymerase sigma factor; Belongs to the sigma-70 factor family.	Sigma factor E processing protein SpoIIGA.	0.677
sigF	spoIIID	CTK_C08860	CTK_C01590	RNA polymerase sigma factor; Belongs to the sigma-70 factor family.	Stage III sporulation protein D.	0.749
sigF	spoIIP	CTK_C08860	CTK_C16780	RNA polymerase sigma factor; Belongs to the sigma-70 factor family.	Stage II sporulation protein P.	0.707
sigF	spoIIR	CTK_C08860	CTK_C01230	RNA polymerase sigma factor; Belongs to the sigma-70 factor family.	Stage II sporulation protein R.	0.694
sigF	spoIVA	CTK_C08860	CTK_C18500	RNA polymerase sigma factor; Belongs to the sigma-70 factor family.	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	0.750
sigG	spo0A	CTK_C18730	CTK_C19430	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	0.860
sigG	spoIIAA	CTK_C18730	CTK_C08840	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.	0.817
sigG	spoIIAB	CTK_C18730	CTK_C08850	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.895
sigG	spoIIE	CTK_C18730	CTK_C29350	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage II sporulation protein E.	0.892
sigG	spoIIGA	CTK_C18730	CTK_C18750	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Sigma factor E processing protein SpoIIGA.	0.882
sigG	spoIIID	CTK_C18730	CTK_C01590	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage III sporulation protein D.	0.806
sigG	spoIIP	CTK_C18730	CTK_C16780	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage II sporulation protein P.	0.759
sigG	spoIIR	CTK_C18730	CTK_C01230	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage II sporulation protein R.	0.810
sigG	spoIVA	CTK_C18730	CTK_C18500	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	0.811
spo0A	sigF	CTK_C19430	CTK_C08860	Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	RNA polymerase sigma factor; Belongs to the sigma-70 factor family.	0.831
spo0A	sigG	CTK_C19430	CTK_C18730	Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.860