STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aspC_1Aspartate aminotransferase. (407 aa)    
Predicted Functional Partners:
gltA
NADPH-dependent glutamate synthase large subunit.
  
 
 0.945
ldh_2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.934
pheA
Prephenate dehydratase.
 
 
 0.925
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.919
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 0.917
metC
Cystathionine beta-lyase.
  
 
 0.916
aspB
Aspartate aminotransferase.
  
  
 
0.915
pyrB
Aspartate carbamoyltransferase, catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
  0.914
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 0.911
tyrA
Prephenate dehydrogenase.
  
 
 0.910
Your Current Organism:
Clostridium tyrobutyricum
NCBI taxonomy Id: 1519
Other names: ATCC 25755, C. tyrobutyricum, CCUG 48315, CIP 105092, Clostridium sp. GPRE 4-2, DSM 2637, JCM 11008
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