STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
engAGTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (489 aa)    
Predicted Functional Partners:
cmk
Pfam:pfam02224 Cytidylate kinase.
  
 0.990
gpsA
Pfam:pfam07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.965
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.900
ALQ56457.1
TPR-like domain-containing protein; Pfam:pfam09976 Tetratricopeptide repeat.
 
    0.872
bamB
Outer membrane protein assembly factor BamB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.865
secA
Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
 
  
 0.861
typA
GTP-binding protein; Pfam:pfam00009 Elongation factor Tu GTP binding domain.
  
  
 0.851
rluB
Pfam:pfam00849 RNA pseudouridylate synthase; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.847
hisS
Histidinol dehydrogenase; Pfam:pfam00587 tRNA synthetase class II core domain (G, H, P, S and T).
 
  
 0.834
ftsY
Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
 
  
 0.803
Your Current Organism:
Pseudoalteromonas issachenkonii
NCBI taxonomy Id: 152297
Other names: CIP 106858, DSM 15925, KCTC 12958, KMM 3549, LMG 19697, LMG:19697, P. issachenkonii, Pseudoalteromonas issachenkonii Ivanova et al. 2002, Pseudoalteromonas sp. F13, Pseudoalteromonas sp. F2, Pseudoalteromonas sp. KMM 3549
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