node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APR07142.1 | APR07513.1 | FAM21731_00941 | FAM21731_01328 | Succinyl-diaminopimelate desuccinylase. | Exodeoxyribonuclease. | 0.519 |
APR07226.1 | APR07513.1 | FAM21731_01027 | FAM21731_01328 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease. | 0.631 |
APR07226.1 | APR08490.1 | FAM21731_01027 | FAM21731_02360 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative A/G-specific adenine glycosylase YfhQ; Adenine glycosylase active on G-A mispairs. | 0.557 |
APR07226.1 | polA | FAM21731_01027 | FAM21731_02249 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.999 |
APR07226.1 | topA | FAM21731_01027 | FAM21731_02405 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.557 |
APR07512.1 | APR07513.1 | FAM21731_01327 | FAM21731_01328 | Hypothetical protein. | Exodeoxyribonuclease. | 0.553 |
APR07513.1 | APR07142.1 | FAM21731_01328 | FAM21731_00941 | Exodeoxyribonuclease. | Succinyl-diaminopimelate desuccinylase. | 0.519 |
APR07513.1 | APR07226.1 | FAM21731_01328 | FAM21731_01027 | Exodeoxyribonuclease. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.631 |
APR07513.1 | APR07512.1 | FAM21731_01328 | FAM21731_01327 | Exodeoxyribonuclease. | Hypothetical protein. | 0.553 |
APR07513.1 | APR08490.1 | FAM21731_01328 | FAM21731_02360 | Exodeoxyribonuclease. | Putative A/G-specific adenine glycosylase YfhQ; Adenine glycosylase active on G-A mispairs. | 0.532 |
APR07513.1 | APR08554.1 | FAM21731_01328 | FAM21731_02428 | Exodeoxyribonuclease. | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | 0.616 |
APR07513.1 | birA | FAM21731_01328 | FAM21731_01771 | Exodeoxyribonuclease. | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.704 |
APR07513.1 | metG | FAM21731_01328 | FAM21731_01835 | Exodeoxyribonuclease. | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.408 |
APR07513.1 | nfo | FAM21731_01328 | FAM21731_02455 | Exodeoxyribonuclease. | Putative endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.575 |
APR07513.1 | polA | FAM21731_01328 | FAM21731_02249 | Exodeoxyribonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.693 |
APR07513.1 | topA | FAM21731_01328 | FAM21731_02405 | Exodeoxyribonuclease. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.494 |
APR08490.1 | APR07226.1 | FAM21731_02360 | FAM21731_01027 | Putative A/G-specific adenine glycosylase YfhQ; Adenine glycosylase active on G-A mispairs. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.557 |
APR08490.1 | APR07513.1 | FAM21731_02360 | FAM21731_01328 | Putative A/G-specific adenine glycosylase YfhQ; Adenine glycosylase active on G-A mispairs. | Exodeoxyribonuclease. | 0.532 |
APR08490.1 | birA | FAM21731_02360 | FAM21731_01771 | Putative A/G-specific adenine glycosylase YfhQ; Adenine glycosylase active on G-A mispairs. | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.423 |
APR08490.1 | polA | FAM21731_02360 | FAM21731_02249 | Putative A/G-specific adenine glycosylase YfhQ; Adenine glycosylase active on G-A mispairs. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.464 |