STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsaDtRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (346 aa)    
Predicted Functional Partners:
APR08155.1
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB.
 
 
 0.989
APR08213.1
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE.
 
 0.951
APR08156.1
Ribosomal-protein-alanine N-acetyltransferase.
  
  
 0.845
APR08154.1
Acyl-ACP thioesterase.
       0.794
rsmA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.766
rsmI
Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.764
pheS
Phenylalanine--tRNA ligase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
 
   
 0.753
APR06307.1
Threonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
  
 
 0.693
ftsH
ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
 
   
 0.683
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.628
Your Current Organism:
Lactobacillus parabuchneri
NCBI taxonomy Id: 152331
Other names: ATCC 49374, CCUG 32261, CIP 103368, CIP 106749 [[Lactobacillus ferintoshensis Simpson et al. 2002]], DSM 5707, JCM 12493, JCM 12511 [[Lactobacillus ferintoshensis Simpson et al. 2002]], L. parabuchneri, LMG 11457, LMG:11457, Lactobacillus ferintoshensis, Lactobacillus ferintoshensis Simpson et al. 2002, NBRC 107865, NCDO 2748, NCIMB 8838, strain R7-84 [[Lactobacillus ferintoshensis Simpson et al. 2002]], strain R7-84(T) [[Lactobacillus ferintoshensis Simpson et al. 2002]]
Server load: low (24%) [HD]